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医学辅助生殖中的不平等:范围综述。

Inequities in Medically Assisted Reproduction: a Scoping Review.

机构信息

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, 1111 W 17Th St, Tulsa, OK, 74107, USA.

Department of Psychiatry and Behavioral Sciences, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.

出版信息

Reprod Sci. 2023 Aug;30(8):2373-2396. doi: 10.1007/s43032-023-01236-6. Epub 2023 Apr 26.

DOI:10.1007/s43032-023-01236-6
PMID:37099229
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10132432/
Abstract

Infertility has a high prevalence in the USA and health inequities play a large role in access to medically assisted reproduction (MAR). The aim of this study was to identify gaps in research pertaining to inequities in MAR and propose suggestions for future research directions. Searches were performed using MEDLINE and Ovid Embase. Articles that reported on MAR inequities, published between 2016 and 2021 in the USA, and written in English were included. The inequities investigated were adapted from the NIH-designated health disparities populations. Each article's inequity findings were extracted and reported, along with frequencies of inequities. Our sample included 66 studies. The majority of the studies investigated MAR outcomes by race/ethnicity and found that historically marginalized populations had poorer outcomes. LGBTQ + populations were less likely to use MAR or seek infertility care. Most studies found positive correlations with MAR use with income and education. The least commonly studied inequities in our sample were sex and/or gender and rural/under-resourced populations; findings showed that men and people from rural/under-resourced populations were less likely to access MAR. Studies that examined occupational status had varying findings. We suggest that future research be targeted toward: (1) standardizing and diversifying race/ethnicity reporting regarding MAR, (2) the use of community-based participatory research to increase data for LGBTQ + patients, and (3) increasing access to infertility care for men.

摘要

不孕症在美国的发病率很高,健康不平等在获得医学辅助生殖(MAR)方面起着重要作用。本研究的目的是确定与 MAR 不平等相关的研究差距,并提出未来研究方向的建议。使用 MEDLINE 和 Ovid Embase 进行了搜索。纳入了 2016 年至 2021 年在美国发表的、以英文撰写的、报告 MAR 不平等的文章。所调查的不平等现象改编自 NIH 指定的健康差异人群。提取并报告了每篇文章的不平等发现,以及不平等现象的频率。我们的样本包括 66 项研究。大多数研究通过种族/族裔调查了 MAR 结果,发现历史上处于边缘地位的人群的结果较差。LGBTQ+人群不太可能使用 MAR 或寻求不孕治疗。大多数研究发现,MAR 的使用与收入和教育呈正相关。在我们的样本中,研究最少的不平等现象是性别和/或性别以及农村/资源不足的人群;研究结果表明,男性和来自农村/资源不足的人群获得 MAR 的机会较少。研究职业状况的研究结果各不相同。我们建议未来的研究针对:(1)标准化和多样化 MAR 种族/族裔报告,(2)使用社区参与性研究为 LGBTQ+患者增加数据,以及(3)增加男性获得不孕治疗的机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b0/10132432/1244352cc94c/43032_2023_1236_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b0/10132432/613793a87826/43032_2023_1236_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b0/10132432/c1008b51dbee/43032_2023_1236_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b0/10132432/1244352cc94c/43032_2023_1236_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b0/10132432/613793a87826/43032_2023_1236_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b0/10132432/c1008b51dbee/43032_2023_1236_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b0/10132432/1244352cc94c/43032_2023_1236_Fig3_HTML.jpg

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Out-of-Pocket Costs for Men Undergoing Infertility Care and Associated Financial Strain.接受不孕不育治疗男性的自付费用及相关经济压力
Urol Pract. 2016 Jul;3(4):256-261. doi: 10.1016/j.urpr.2015.07.010. Epub 2016 Apr 21.
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Race/ethnicity reporting and representation in US clinical trials: a cohort study.美国临床试验中的种族/族裔报告与代表性:一项队列研究。
Lancet Reg Health Am. 2022 Jul;11. doi: 10.1016/j.lana.2022.100252. Epub 2022 Apr 10.
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Access to Fertility Care in Geographically Underserved Populations, a Second Look.地理上服务不足人群的生育护理获取,再探。
Reprod Sci. 2022 Jul;29(7):1983-1987. doi: 10.1007/s43032-022-00991-2. Epub 2022 Jun 9.
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Racial disparities in frozen embryo transfer success.冷冻胚胎移植成功率的种族差异。
J Assist Reprod Genet. 2021 Dec;38(12):3069-3075. doi: 10.1007/s10815-021-02348-1. Epub 2021 Nov 5.
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Trends in Infertility Care Among Commercially Insured US Women During the COVID-19 Pandemic.新冠疫情期间商业保险覆盖的美国女性不孕护理趋势。
JAMA Netw Open. 2021 Oct 1;4(10):e2128520. doi: 10.1001/jamanetworkopen.2021.28520.
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Prevalence and characteristics of patients declined from pursuing in vitro fertilization with autologous oocytes.自愿放弃使用自身卵子进行体外受精治疗患者的比例及特征。
J Assist Reprod Genet. 2021 Oct;38(10):2679-2685. doi: 10.1007/s10815-021-02287-x. Epub 2021 Aug 10.
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Incidence of Infertility and Pregnancy Complications in US Female Surgeons.美国女外科医生的不孕和妊娠并发症发生率
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