Free University of Brussels, 808 Route de Lennik, B-1070, Brussels, Belgium.
Department of Internal Medicine, Institute for Lung Health, Cardiopulmonary Institute and Deutsches Zentrum Für LungenforschunUniversities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany.
Curr Heart Fail Rep. 2023 Jun;20(3):208-217. doi: 10.1007/s11897-023-00599-w. Epub 2023 Apr 26.
Tricuspid regurgitation is associated with increased mortality in proportion to right ventricular adaptation to increased volume loading and pulmonary artery pressure. We here review recent progress in the understanding of right ventricular adaptation to pre- and after-loading conditions for improved recommendations of tricuspid valve repair.
Trans-catheter tricuspid valve repair has made the correction of tricuspid regurgitation more easily available, triggering a need of tighter indications. Several studies have shown the feasibility and relevance to the indications of tricuspid valve repair of imaging of right ventricular ejection fraction measured by magnetic resonance imaging or 3D-echocardiography, and the 2D-echocardiography of the tricuspid annular plane systolic excursion to systolic pulmonary artery pressure ratio combined with invasively determined mean pulmonary artery pressure and pulmonary vascular resistance. Improved definitions of right ventricular failure and pulmonary hypertension may be considered in future recommendations on the treatment of tricuspid regurgitation.
三尖瓣反流与死亡率呈正相关,与右心室对增加的容量负荷和肺动脉压力的适应性成比例。我们在此回顾了右心室对前负荷和后负荷适应的最新研究进展,以更好地推荐三尖瓣修复。
经导管三尖瓣修复术使三尖瓣反流的矫正更容易实现,引发了对更严格适应证的需求。几项研究表明,通过磁共振成像或三维超声心动图测量右心室射血分数的影像学检查,以及二维超声心动图测量三尖瓣环平面收缩期位移与收缩期肺动脉压的比值,并结合有创性测定平均肺动脉压和肺血管阻力,对三尖瓣修复适应证的可行性和相关性具有重要意义。在未来关于三尖瓣反流治疗的建议中,可以考虑对右心衰竭和肺动脉高压的定义进行改进。