Center of Pathophysiology, Infectiology and Immunology, Institute of Specific Prophylaxis and Tropical Medicine, Medical University Vienna, Vienna, Austria.
Center of Pathophysiology, Infectiology and Immunology, Division of Infection Diagnosis and Infectious Disease Epidemiology, Medical University Vienna, Vienna, Austria.
Euro Surveill. 2023 Apr;28(17). doi: 10.2807/1560-7917.ES.2023.28.17.2300206.
Following an increase in diphtheria cases in Europe since 2022, we retrospectively estimated the prevalence of seroprotection against diphtheria and tetanus in 10,247 Austrian residents (population: 8,978,929) voluntarily tested between 2018 and 2022. Lack of seroprotection against diphtheria was found in 36% compared with 4% against tetanus. The geometric mean antibody concentration against tetanus was 7.9-fold higher compared with that for diphtheria. Raising awareness of regular booster vaccinations against diphtheria in combination with tetanus and pertussis is urgently needed.
自 2022 年以来，欧洲白喉病例有所增加，我们对 2018 年至 2022 年间自愿检测的 10247 名奥地利居民（人口：8978929 人）对白喉和破伤风的血清保护率进行了回顾性估计。与破伤风相比，发现对白喉无血清保护的比例为 36%，而破伤风为 4%。破伤风的几何平均抗体浓度比白喉高 7.9 倍。迫切需要提高对白喉、破伤风和百日咳定期加强免疫接种的认识。
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