Linkou Chang Gung Memorial Hospital, Taoyuan City, Taiwan.
Department of Secretariat, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan.
Sci Rep. 2023 Apr 27;13(1):6891. doi: 10.1038/s41598-023-33410-w.
The multitude of fixation options for radial neck fractures, such as pins, screws, biodegradable pins and screws, locking plates, and blade plates, has led to a lack of consensus on the optimal implant choice and associated biomechanical properties. This study aims to evaluate the biomechanical strength of various fixation constructs in axial, sagittal, and torsional loading directions. We included biomechanical studies comparing different interventions, such as cross/parallel screws, nonlocking plates with or without augmented screws, fixed angle devices (T or anatomic locking plates or blade plates), and cross pins. A systematic search of MEDLINE (Ovid), Embase, Scopus, and CINAHL EBSCO databases was conducted on September 26th, 2022. Data extraction was carried out by one author and verified by another. A network meta-analysis (NMA) was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Primary outcomes encompassed axial, bending, and torsional stiffness, while the secondary outcome was bending load to failure. Effect sizes were calculated for continuous outcomes, and relative treatment ranking was measured using the surface under the cumulative ranking curve (SUCRA). Our analysis encompassed eight studies, incorporating 172 specimens. The findings indicated that fixed angle constructs, specifically the anatomic locking plate, demonstrated superior axial stiffness (mean difference [MD]: 23.59 N/mm; 95% CI 8.12-39.06) in comparison to the cross screw. Additionally, the blade plate construct excelled in bending stiffness (MD: 32.37 N/mm; 95% CI - 47.37 to 112.11) relative to the cross screw construct, while the cross-screw construct proved to be the most robust in terms of bending load failure. The parallel screw construct performed optimally in torsional stiffness (MD: 139.39 Nm/degree; 95% CI 0.79-277.98) when compared to the cross screw construct. Lastly, the nonlocking plate, locking T plate, and cross-pin constructs were found to be inferior in most respects to alternative interventions. The NMA indicated that fixed angle devices (blade plate and anatomic locking plate) and screw fixations may exhibit enhanced biomechanical strength in axial and bending directions, whereas cross screws demonstrated reduced torsional stability in comparison to parallel screws. It is imperative for clinicians to consider the application of these findings in constraining forces across various directions during early range of motion exercises, taking into account the distinct biomechanical properties of the respective implants.
桡骨颈骨折的固定选择众多,如钢针、螺钉、可吸收钢针和螺钉、锁定板和 blade 板等,这导致对于最佳植入物选择和相关生物力学特性缺乏共识。本研究旨在评估各种固定结构在轴向、矢状和扭转加载方向上的生物力学强度。我们纳入了比较不同干预措施的生物力学研究,如交叉/平行螺钉、有无增强螺钉的非锁定板、固定角度装置(T 型或解剖锁定板或 blade 板)和交叉钢针。于 2022 年 9 月 26 日对 MEDLINE(Ovid)、Embase、Scopus 和 CINAHL EBSCO 数据库进行了系统检索。由一位作者进行数据提取,并由另一位作者进行验证。根据系统评价和荟萃分析的首选报告项目进行了网络荟萃分析(NMA)。主要结局包括轴向、弯曲和扭转刚度,次要结局为弯曲失效载荷。对连续结局进行效应量计算,使用累积排序曲线下面积(SUCRA)测量相对治疗排名。我们的分析包括八项研究,共纳入 172 个标本。结果表明,与交叉螺钉相比,固定角度结构,特别是解剖锁定板,在轴向刚度方面表现出优势(平均差异 [MD]:23.59 N/mm;95%CI 8.12-39.06)。此外,与交叉螺钉结构相比,blade 板结构在弯曲刚度方面表现出色(MD:32.37 N/mm;95%CI -47.37 至 112.11),而交叉螺钉结构在弯曲失效载荷方面表现最佳。与交叉螺钉结构相比,平行螺钉结构在扭转刚度方面表现最佳(MD:139.39 Nm/度;95%CI 0.79-277.98)。最后,非锁定板、锁定 T 板和交叉钢针结构在大多数方面都不如其他干预措施。NMA 表明,固定角度装置(blade 板和解剖锁定板)和螺钉固定可能在轴向和弯曲方向上表现出增强的生物力学强度,而与平行螺钉相比,交叉螺钉表现出降低的扭转稳定性。临床医生在早期活动范围内考虑到不同植入物的特定生物力学特性时,考虑到这些发现在各个方向上的约束力量的应用至关重要。