Meryn S, Stein D, Straus E W
Int J Obes. 1986;10(1):37-42.
The influence of morbid obesity and gastric bypass operation on pancreatic polypeptide (PP), pancreatic glucagon and enteroglucagon was studied in six morbidly obese patients before and 6-9 months after surgery. Hormone plasma levels were determined in the fasting state and after a standardized test meal. Fasting levels of PP, pancreatic glucagon and enteroglucagon were not significantly different between the pre- and post-operative state as well as compared to normal controls. The postprandial response showed a significant reduction of PP, a significant increase of enteroglucagon and no change of pancreatic glucagon after surgery compared with the preoperative values.
研究了6例病态肥胖患者在手术前以及手术后6 - 9个月，病态肥胖和胃旁路手术对胰多肽（PP）、胰高血糖素和肠高血糖素的影响。在空腹状态和标准化试餐后测定激素血浆水平。术前和术后状态以及与正常对照组相比，PP、胰高血糖素和肠高血糖素的空腹水平无显著差异。与术前值相比，术后餐后反应显示PP显著降低，肠高血糖素显著增加，胰高血糖素无变化。
