Amland P F, Jorde R, Giercksky K E, Burhol P G
Int J Obes. 1984;8(2):117-22.
The diurnal gastric inhibitory polypeptide (GIP), pancreatic polypeptide (PP) and insulin levels in eight morbidly obese subjects were studied before and four weeks and five months after a stapled gastric partitioning. The integrated release of all three peptides was significantly reduced postoperatively, although the profiles of the plasma GIP and PP curves were similar. On the other hand, the diurnal insulin pattern was changed from a pathological prolonged hyperinsulinemia starting shortly after breakfast and lasting till late in the evening, to a normal pattern with small, shortlived postprandial peaks.
对8名病态肥胖受试者在进行吻合器胃分隔术前、术后4周和5个月时的日间胃抑制性多肽（GIP）、胰多肽（PP）和胰岛素水平进行了研究。尽管血浆GIP和PP曲线的形态相似，但术后这三种肽的整体释放均显著减少。另一方面，日间胰岛素模式从早餐后不久开始并持续至傍晚的病理性长期高胰岛素血症，转变为餐后出现小的、短暂峰值的正常模式。
