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恢复力、压力和皮质醇可预测老年人的认知表现。

Resilience, Stress, and Cortisol Predict Cognitive Performance in Older Adults.

作者信息

Saez-Sanz Noelia, Peralta-Ramirez Isabel, Gonzalez-Perez Raquel, Vazquez-Justo Enrique, Caracuel Alfonso

机构信息

Mind, Brain, and Behavior Research Center (CIMCYC), University of Granada, 18071 Granada, Spain.

Department of Psychology and Anthropology, University of Extremadura, 06006 Badajoz, Spain.

出版信息

Healthcare (Basel). 2023 Apr 9;11(8):1072. doi: 10.3390/healthcare11081072.

Abstract

OBJECTIVE

to determine the relationship between stress, resilience, and cognitive performance in older people without dementia.

METHOD

multiple linear regressions were performed using measures of cognitive performance as dependent variables, and measures of stress and resilience as predictors in a sample of 63 Spanish elderly people.

RESULTS

participants reported low levels of stress during their lifetime. In addition to socio-demographic variables, greater stress was related to better delayed recall and worse letter-number sequencing and block design. Higher capillary cortisol was associated with lower flexibility on the Stroop task. Regarding protective factors, we found that greater psychological resilience was related to higher scores on the Addenbrooke's Cognitive Examination-III, letter-number sequencing, and verbal fluency.

CONCLUSION

in older people with low stress, apart from age, gender, and education, psychological resilience is a significant predictor of global cognitive status, working memory, and fluency. Likewise, stress is related to verbal memory functioning, working memory, and visuoconstructive abilities. Capillary cortisol level predicts cognitive flexibility. These findings may help to identify risk and protective factors for cognitive decline in older people. Training-based programs to reduce stress and increase psychological resilience may play an important role in preventing cognitive decline.

摘要

目的

确定无痴呆症老年人的压力、心理韧性与认知表现之间的关系。

方法

在63名西班牙老年人样本中,以认知表现测量值为因变量,压力和心理韧性测量值为预测变量进行多元线性回归分析。

结果

参与者报告其一生中压力水平较低。除社会人口统计学变量外,更大的压力与更好的延迟回忆、更差的数字-字母排序及积木设计表现有关。更高的毛细血管皮质醇水平与斯特鲁普任务中更低的灵活性相关。关于保护因素,我们发现更强的心理韧性与Addenbrooke认知检查-III、数字-字母排序及语言流畅性方面的更高得分有关。

结论

在压力水平较低的老年人中,除年龄、性别和教育程度外,心理韧性是整体认知状态、工作记忆和流畅性的重要预测因素。同样,压力与言语记忆功能、工作记忆和视觉构建能力有关。毛细血管皮质醇水平可预测认知灵活性。这些发现可能有助于识别老年人认知衰退的风险和保护因素。基于训练的减轻压力和增强心理韧性的项目可能在预防认知衰退中发挥重要作用。

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本文引用的文献

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A framework for concepts of reserve and resilience in aging.衰老储备和恢复力的概念框架。
Neurobiol Aging. 2023 Apr;124:100-103. doi: 10.1016/j.neurobiolaging.2022.10.015. Epub 2022 Dec 19.

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