Kutarski Andrzej, Jacheć Wojciech, Polewczyk Anna, Nowosielecka Dorota
Department of Cardiology, Medical University, 20-059 Lublin, Poland.
2nd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 41-800 Zabrze, Poland.
J Clin Med. 2023 Apr 13;12(8):2837. doi: 10.3390/jcm12082837.
The long-term significance of lead remnants (LR) following transvenous lead extraction (TLE) remains disputable, especially in infectious patients.
Retrospective analysis of 3741 TLEs focused on the relationship between LR and procedure complexity, complications and long-term survival.
The study group consisted of 156 individuals with LR (4.17%), and the control group consisted of 3585 patients with completely removed lead(s). In a multivariable model, a younger patient age at CIED implantation, more CIED procedures and procedure complexity were independent risk factors for retention of non-removable LR. Although patients with LR showed better survival outcomes following TLE (log rank = 0.041 for non-infectious group and = 0.017 for infectious group), multivariable Cox regression analysis did not confirm the prognostic significance of LR either in non-infectious [HR = 0.777; = 0.262], infectious [HR = 0.983; = 0.934] or the entire group of patients [HR = 0.858; = 0.321].
经静脉导线拔除术(TLE)后导线残留(LR)的长期意义仍存在争议,尤其是在感染患者中。
对3741例TLE进行回顾性分析,重点关注LR与手术复杂性、并发症及长期生存之间的关系。
研究组由156例有LR的患者组成(4.17%),对照组由3585例导线完全拔除的患者组成。在多变量模型中,心脏植入电子装置(CIED)植入时患者年龄较小、更多的CIED手术及手术复杂性是非可移除LR残留的独立危险因素。尽管有LR的患者在TLE后显示出更好的生存结果(非感染组对数秩检验=0.041,感染组=0.017),但多变量Cox回归分析未证实LR在非感染患者[风险比(HR)=0.777;P=0.262]、感染患者[HR=0.983;P=0.934]或整个患者组[HR=0.858;P=0.321]中的预后意义。