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拔牙过程中铅去除不完全:感染性和非感染性病例的易感因素及对长期生存的影响:3741例手术分析

Incomplete Lead Removal During the Extraction Procedure: Predisposing Factors and Impact on Long-Term Survival in Infectious and Non-Infectious Cases: Analysis of 3741 Procedures.

作者信息

Kutarski Andrzej, Jacheć Wojciech, Polewczyk Anna, Nowosielecka Dorota

机构信息

Department of Cardiology, Medical University, 20-059 Lublin, Poland.

2nd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 41-800 Zabrze, Poland.

出版信息

J Clin Med. 2023 Apr 13;12(8):2837. doi: 10.3390/jcm12082837.

DOI:10.3390/jcm12082837
PMID:37109174
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10144379/
Abstract

BACKGROUND

The long-term significance of lead remnants (LR) following transvenous lead extraction (TLE) remains disputable, especially in infectious patients.

METHODS

Retrospective analysis of 3741 TLEs focused on the relationship between LR and procedure complexity, complications and long-term survival.

RESULTS

The study group consisted of 156 individuals with LR (4.17%), and the control group consisted of 3585 patients with completely removed lead(s). In a multivariable model, a younger patient age at CIED implantation, more CIED procedures and procedure complexity were independent risk factors for retention of non-removable LR. Although patients with LR showed better survival outcomes following TLE (log rank = 0.041 for non-infectious group and = 0.017 for infectious group), multivariable Cox regression analysis did not confirm the prognostic significance of LR either in non-infectious [HR = 0.777; = 0.262], infectious [HR = 0.983; = 0.934] or the entire group of patients [HR = 0.858; = 0.321].

CONCLUSIONS

  1. Non-removable LRs are encountered in 4.17% of patients. 2. CIED infection has no influence on retention of LRs, but younger patient age, multiple CIED-related procedures and higher levels of procedure complexity are independent risk factors for the presence of LR. 3. Better survival outcomes following TLE in patients with LRs are not the effects of their presence but younger patient and better health status.
摘要

背景

经静脉导线拔除术(TLE)后导线残留(LR)的长期意义仍存在争议,尤其是在感染患者中。

方法

对3741例TLE进行回顾性分析,重点关注LR与手术复杂性、并发症及长期生存之间的关系。

结果

研究组由156例有LR的患者组成(4.17%),对照组由3585例导线完全拔除的患者组成。在多变量模型中,心脏植入电子装置(CIED)植入时患者年龄较小、更多的CIED手术及手术复杂性是非可移除LR残留的独立危险因素。尽管有LR的患者在TLE后显示出更好的生存结果(非感染组对数秩检验=0.041,感染组=0.017),但多变量Cox回归分析未证实LR在非感染患者[风险比(HR)=0.777;P=0.262]、感染患者[HR=0.983;P=0.934]或整个患者组[HR=0.858;P=0.321]中的预后意义。

结论

  1. 4.17%的患者存在非可移除的LR。2. CIED感染对LR的残留无影响,但患者年龄较小、多次CIED相关手术及更高水平的手术复杂性是LR存在的独立危险因素。3. 有LR的患者TLE后更好的生存结果并非其存在的影响,而是患者年龄较小及健康状况较好所致。
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d6/10144379/b7e2df2dc720/jcm-12-02837-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d6/10144379/b7e2df2dc720/jcm-12-02837-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d6/10144379/b7e2df2dc720/jcm-12-02837-g001a.jpg

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本文引用的文献

1
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Sci Rep. 2022 Jun 10;12(1):9601. doi: 10.1038/s41598-022-13769-y.
2
The role of cardiac surgeon in transvenous lead extraction: Experience from 3462 procedures.心脏外科医生在经静脉导线拔除术中的作用:3462 例手术经验。
J Cardiovasc Electrophysiol. 2022 Jul;33(7):1357-1365. doi: 10.1111/jce.15510. Epub 2022 May 6.
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Transvenous Lead Extraction in Patients with Cardiac Implantable Device: The Impact of Systemic and Local Infection on Clinical Outcomes-An ESC-EHRA ELECTRa (European Lead Extraction Controlled) Registry Substudy.
心脏植入式设备患者的经静脉导线拔除:全身和局部感染对临床结局的影响——一项欧洲心脏病学会-欧洲心律协会ELECTRa(欧洲导线拔除对照)注册研究的子研究
Biology (Basel). 2022 Apr 18;11(4):615. doi: 10.3390/biology11040615.
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Predictors of lead break during transvenous lead extraction.经静脉导线拔除术中导线断裂的预测因素。
J Arrhythm. 2021 Mar 15;37(3):645-652. doi: 10.1002/joa3.12524. eCollection 2021 Jun.
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Long-term survival following transvenous lead extraction: Importance of indication and comorbidities.经静脉导线拔除后的长期生存:适应证和合并症的重要性。
Heart Rhythm. 2021 Sep;18(9):1566-1576. doi: 10.1016/j.hrthm.2021.05.007. Epub 2021 May 10.
6
Transesophageal Echocardiography As a Monitoring Tool During Transvenous Lead Extraction-Does It Improve Procedure Effectiveness?经食管超声心动图作为经静脉导线拔除术中的监测工具——它能提高手术效果吗?
J Clin Med. 2020 May 8;9(5):1382. doi: 10.3390/jcm9051382.
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The MB score: a new risk stratification index to predict the need for advanced tools in lead extraction procedures.MB 评分:一种新的风险分层指数,用于预测在导线提取程序中需要使用高级工具的情况。
Europace. 2020 Apr 1;22(4):613-621. doi: 10.1093/europace/euaa027.
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Europace. 2019 May 1;21(5):771-780. doi: 10.1093/europace/euy300.
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