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柬埔寨疫苗公平性的多变量评估:使用2004年、2010年和2014年人口与健康调查的纵向VERSE工具案例研究

Multivariate Assessment of Vaccine Equity in Cambodia: A Longitudinal VERSE Tool Case Study Using Demographic and Health Survey 2004, 2010, and 2014.

作者信息

Zhao Yijin, Mak Joshua, de Broucker Gatien, Patenaude Bryan

机构信息

International Vaccine Access Center, Johns Hopkins University, Baltimore, MD 21231, USA.

Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.

出版信息

Vaccines (Basel). 2023 Apr 4;11(4):795. doi: 10.3390/vaccines11040795.

Abstract

Cambodia has exhibited great progress in achieving high coverage in nationally recommended immunizations. As vaccination program managers plan interventions to reach last-mile children, it is important to consider issues of equity immunization priority setting. In this analysis, we apply the VERSE Equity Tool to Cambodia's Demographic and Health Survey for the years 2004, 2010, and 2014 to evaluate multivariate equity in vaccine coverage for 11 vaccination statuses, emphasizing the results of the 2014 survey for MCV1, DTP3, fully immunized for age (FULL), and zero dose (ZERO). The largest drivers of vaccination inequity are socioeconomic status and the educational attainment of the child's mother. MCV1, DTP3, and FULL exhibit increasing levels of both coverage and equity with increasing survey years. The national composite Wagstaff concentration index values from the 2014 survey for DTP3, MCV1, ZERO, and FULL are 0.089, 0.068, 0.573, and 0.087, respectively. The difference in vaccination status coverage between the most and least advantaged quintiles of Cambodia's population, using multivariate ranking criteria, is 23.5% for DTP3, 19.5% for MCV1, 9.1% for ZERO, and 30.3% for FULL. By utilizing these VERSE Equity Tool outputs, immunization program leaders in Cambodia can identify subnational regions in need of targeted interventions.

摘要

柬埔寨在实现国家推荐免疫接种的高覆盖率方面取得了巨大进展。随着疫苗接种项目管理者规划干预措施以覆盖最后一公里的儿童,考虑免疫接种公平性优先级设定问题非常重要。在本分析中,我们将VERSE公平性工具应用于柬埔寨2004年、2010年和2014年的人口与健康调查,以评估11种疫苗接种状态的疫苗覆盖率的多变量公平性,重点关注2014年关于第一剂麻疹风疹联合疫苗(MCV1)、第三剂白喉破伤风百日咳联合疫苗(DTP3)、按年龄全程免疫(FULL)和零剂次(ZERO)的调查结果。疫苗接种不公平的最大驱动因素是社会经济地位和儿童母亲的教育程度。随着调查年份的增加,MCV1、DTP3和FULL的覆盖率和公平性水平都在提高。2014年调查中DTP3、MCV1、ZERO和FULL的全国综合瓦格斯塔夫集中指数值分别为0.089、0.068、0.573和0.087。根据多变量排名标准,柬埔寨人口中最具优势和最不具优势的五分之一人群在疫苗接种状态覆盖率上的差异,DTP3为23.5%,MCV1为19.5%,ZERO为9.1%,FULL为30.3%。通过利用这些VERSE公平性工具的输出结果,柬埔寨的免疫接种项目负责人可以确定需要有针对性干预措施的次国家级区域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5022/10144395/4d64abde7e9e/vaccines-11-00795-g001.jpg

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