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本文引用的文献

1
Production of Clostridium difficile antitoxin.艰难梭菌抗毒素的生产
Infect Immun. 1980 Jun;28(3):1041-3. doi: 10.1128/iai.28.3.1041-1043.1980.
2
Relative frequency of Clostridium difficile in patients with diarrheal disease.腹泻病患者中艰难梭菌的相对频率。
J Clin Microbiol. 1981 Jul;14(1):26-31. doi: 10.1128/jcm.14.1.26-31.1981.
3
Latex agglutination test for detection of Clostridium difficile toxin in stool samples.用于检测粪便样本中艰难梭菌毒素的乳胶凝集试验。
J Clin Microbiol. 1984 Sep;20(3):339-41. doi: 10.1128/jcm.20.3.339-341.1984.
4
Enzyme-linked immunosorbent assay for Clostridium difficile toxin A.艰难梭菌毒素A的酶联免疫吸附测定
J Clin Microbiol. 1983 Jan;17(1):72-8. doi: 10.1128/jcm.17.1.72-78.1983.
5
Monoclonal and specific polyclonal antibodies for immunoassay of Clostridium difficile toxin A.用于艰难梭菌毒素A免疫测定的单克隆抗体和特异性多克隆抗体。
J Clin Microbiol. 1985 Jan;21(1):12-4. doi: 10.1128/jcm.21.1.12-14.1985.
6
Colitis induced by Clostridium difficile.艰难梭菌引起的结肠炎。
Rev Infect Dis. 1979 Mar-Apr;1(2):370-8. doi: 10.1093/clinids/1.2.370.

用于检测艰难梭菌毒素的商业细胞毒性检测方法的评估

Evaluation of a commercial cytotoxicity assay for detection of Clostridium difficile toxin.

作者信息

Nachamkin I, Lotz-Nolan L, Skalina D

出版信息

J Clin Microbiol. 1986 May;23(5):954-5. doi: 10.1128/jcm.23.5.954-955.1986.

DOI:10.1128/jcm.23.5.954-955.1986
PMID:3711282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC268758/
Abstract

A comparative study was performed to determine the accuracy of Clostridium difficile toxin detection. A commercial cytotoxicity assay (Bartels Immunodiagnostic Supply, Bellevue, Wash.) was compared with conventional microcytotoxicity assays, using Vero and MRC-5 cells. The Bartels system was found to be essentially equivalent to conventional cytotoxicity assays currently being performed for routine C. difficile toxin detection.

摘要

进行了一项比较研究以确定艰难梭菌毒素检测的准确性。使用Vero细胞和MRC - 5细胞，将一种商业细胞毒性检测方法（巴特尔免疫诊断用品公司，华盛顿州贝尔维尤）与传统的微细胞毒性检测方法进行了比较。发现巴特尔系统与目前用于常规艰难梭菌毒素检测的传统细胞毒性检测方法基本等效。