用于检测艰难梭菌毒素的商业细胞毒性检测方法的评估
Evaluation of a commercial cytotoxicity assay for detection of Clostridium difficile toxin.
作者信息
Nachamkin I, Lotz-Nolan L, Skalina D
出版信息
J Clin Microbiol. 1986 May;23(5):954-5. doi: 10.1128/jcm.23.5.954-955.1986.
Abstract
A comparative study was performed to determine the accuracy of Clostridium difficile toxin detection. A commercial cytotoxicity assay (Bartels Immunodiagnostic Supply, Bellevue, Wash.) was compared with conventional microcytotoxicity assays, using Vero and MRC-5 cells. The Bartels system was found to be essentially equivalent to conventional cytotoxicity assays currently being performed for routine C. difficile toxin detection.
摘要
进行了一项比较研究以确定艰难梭菌毒素检测的准确性。使用Vero细胞和MRC - 5细胞，将一种商业细胞毒性检测方法（巴特尔免疫诊断用品公司，华盛顿州贝尔维尤）与传统的微细胞毒性检测方法进行了比较。发现巴特尔系统与目前用于常规艰难梭菌毒素检测的传统细胞毒性检测方法基本等效。
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