针对胶质纤维酸性蛋白（GFAP）的特异性单克隆抗体。
Specific monoclonal antibodies to glial fibrillary acidic protein (GFAP).
作者信息
Courel M N, Girard N, Delpech B, Chauzy C
出版信息
J Neuroimmunol. 1986 Jun;11(4):271-6. doi: 10.1016/0165-5728(86)90080-9.
PMID:3711313
Abstract
Anti-glial fibrillary acidic protein (GFAP) monoclonal antibody has been obtained by fusing SP2/O myeloma cells with splenic cells from mice immunized with human GFAP. It belongs to the IgG1 class and it recognizes an epitope on GFAP which is shared by each fragment of the protein. Immunohistological studies show that the epitope characterized is absolutely specific for GFAP.
摘要
抗胶质纤维酸性蛋白（GFAP）单克隆抗体是通过将SP2/O骨髓瘤细胞与用人GFAP免疫的小鼠脾细胞融合而获得的。它属于IgG1类，识别GFAP上的一个表位，该表位为该蛋白的每个片段所共有。免疫组织学研究表明，所鉴定的表位对GFAP具有绝对特异性。
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