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埃塞俄比亚西北部贡德尔大学综合专科医院癌症患者的中心性肥胖及其相关因素。

Central obesity and its associated factors among cancer patients at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.

作者信息

Molla Meseret Derbew, Wolde Haileab Fekadu, Tafesse Teferi Ephrem, Kibret Anteneh Ayelign

机构信息

Department of Biochemistry, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

出版信息

Front Oncol. 2023 Apr 12;13:1150303. doi: 10.3389/fonc.2023.1150303. eCollection 2023.

Abstract

PURPOSE

Obesity, especially the hidden type of obesity (central obesity), has been believed to be the major risk factor for developing and progressing non-communicable diseases, including cancers. However, there are limited studies regarding the issue in Ethiopia and the study area. Therefore, this study aimed to evaluate the magnitude of central obesity and its associated factors among cancer patients visited the oncology unit of the University of Gondar Comprehensive Specialized Hospital.

METHODS

An institutional-based cross-sectional study was conducted from January 10 to March 10, 2021. A total of 384 study participants were enrolled using a systematic sampling technique. The data were collected using a semi-structured interviewer-administered questionnaire and were pretested to address the quality of assurance. The weight of the participants was assessed using body mass index (BMI) and central obesity. Both bivariate and multivariate logistic regressions were conducted to identify the factors associated with central obesity, and p-values less than 0.05 with multivariate were considered statistically significant associations.

RESULT

Most respondents (60.16%) were stage I cancer patients. The study found that about 19.27% of the participants were prevalent central obesity, and none of them were obese by body mass index (BMI) categorization criteria. However, about 12.24% and 7.03% of the participants were found to be underweight and overweight, respectively. The variables associated with central obesity were sex (AOR=14.40; 95% CI: 5.26 - 39.50), occupation (AOR=4.32; 95%CI: 1.10 - 17.01), and residency (AOR=0.30; 95% CI: 0.13 - 0.70).

CONCLUSION

A significant number of the respondents (19.27%) were centrally obese. Being female, urban residency and having an occupation other than a farmer, merchant, and governmental were the factors associated with central obesity. Hence, cancer patients may be centrally obese with average body weight.

摘要

目的

肥胖,尤其是隐性肥胖(中心性肥胖),被认为是包括癌症在内的非传染性疾病发生和发展的主要危险因素。然而,在埃塞俄比亚及本研究区域,关于该问题的研究有限。因此,本研究旨在评估贡德尔大学综合专科医院肿瘤科就诊的癌症患者中中心性肥胖的程度及其相关因素。

方法

于2021年1月10日至3月10日进行了一项基于机构的横断面研究。采用系统抽样技术共纳入384名研究参与者。通过半结构化访谈问卷收集数据,并进行预测试以确保质量。使用体重指数(BMI)和中心性肥胖评估参与者的体重。进行双变量和多变量逻辑回归以确定与中心性肥胖相关的因素,多变量分析中p值小于0.05被认为具有统计学意义的关联。

结果

大多数受访者(60.16%)为I期癌症患者。研究发现,约19.27%的参与者存在中心性肥胖,根据体重指数(BMI)分类标准,他们均无肥胖情况。然而,分别有约12.24%和7.03%的参与者体重过轻和超重。与中心性肥胖相关的变量有性别(调整后比值比[AOR]=14.40;95%置信区间[CI]:5.26 - 39.50)、职业(AOR=4.32;95%CI:1.10 - 17.01)和居住地(AOR=0.30;95%CI:0.13 - 0.70)。

结论

相当数量的受访者(19.27%)存在中心性肥胖。女性、城市居住以及职业不是农民、商人或政府工作人员是与中心性肥胖相关的因素。因此,癌症患者可能体重正常但存在中心性肥胖。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/080b/10130526/ac28c2c95089/fonc-13-1150303-g001.jpg

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