Department of Ophthalmology and Optometry (Y.Y., Y.X., F.L., X.Z., J.Z.), Eye & ENT Hospital, Fudan University, Shanghai, China; NHC Key Laboratory of Myopia (Fudan University) (Y.Y., Y.X., F.L., X.Z., J.Z.), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry (Y.Y., Y.X., F.L., X.Z., J.Z.), Shanghai, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care (20DZ2255000) (Y.Y., Y.X., F.L., X.Z., J.Z.)Division of Arts and Sciences (Z.-L.L.), NYU Shanghai, Shanghai, China; Center for Neural Science and Department of Psychology, New York University, New York; NYU-ECNU Institute of Brain and Cognitive Science, NYU Shanghai, Shanghai, China.
Eye Contact Lens. 2023 Jun 1;49(6):224-233. doi: 10.1097/ICL.0000000000000995. Epub 2023 Apr 28.
To investigate the characteristics of quick contrast sensitivity function (qCSF) and its related parameters in Chinese ametropia children.
This case series study enrolled 106 eyes of 53 children (male/female=29/24, age: 9.04±2.06 years). Examinations included manifest refraction, axial length, corneal curvature, and monocular and binocular qCSF readings without refractive correction (area under log CSF [AULCSF], CSF acuity, and contrast sensitivity [CS] at 1.0 to 18.0 cpd). The subjects were divided into groups according to age and refractive parameters for analysis.
The mean spherical equivalent (SE), AULCSF, and CSF acuity of the test eyes were -0.94±1.53 D, 0.44±0.33, and 8.50±5.97 cpd, respectively. In the monocular qCSF comparison, the refraction sphere (RS) was the major factor correlated with qCSF readings (B=0.186, P =0.009 for AULCSF; B=0.543, P =0.019 for CSF acuity; generalized linear model). The three groups stratified by RS/SE (<-1.00D, -1.00D to 0D, and >0D) showed significant differences in CS at medium spatial frequencies (3.0 and 6.0 cpd; all P <0.05). In the low RS/SE group (within -1 to 0 D), the CS at 12.0 cpd was significantly lower than that in the hyperopia group (all P <0.05). Binocular qCSF readings were significantly correlated with those of the eyes with lower RS (all P <0.05).
RS and SE are the major contributing factors of qCSF without refractive correction in children. The CS at medium spatial frequencies decrease significantly as the RS/SE increase. In low myopia children, the CS at medium and high spatial frequencies are significantly decreased, providing practical value in visual function screening in children.
探讨中国近视儿童快速对比敏感度功能（qCSF）及其相关参数的特点。
本病例系列研究纳入了 53 名儿童的 106 只眼（男/女=29/24，年龄：9.04±2.06 岁）。检查包括主觉验光、眼轴长度、角膜曲率以及单眼和双眼 qCSF 读数（不矫正屈光状态）（对数 CSF 下面积[AULCSF]、CS 敏锐度和 1.0 至 18.0 cpd 的对比敏感度[CS]）。根据年龄和屈光参数将受试者分为组进行分析。
受试眼的平均球镜（SE）、AULCSF 和 CSF 敏锐度分别为-0.94±1.53 D、0.44±0.33 和 8.50±5.97 cpd。在单眼 qCSF 比较中，屈光球镜（RS）是与 qCSF 读数相关的主要因素（AULCSF 的 B=0.186，P=0.009；CS 敏锐度的 B=0.543，P=0.019；广义线性模型）。按 RS/SE（<-1.00D、-1.00D 至 0D 和>0D）分层的三组在中空间频率（3.0 和 6.0 cpd；均 P<0.05）的 CS 存在显著差异。在低 RS/SE 组（-1 至 0 D 内），12.0 cpd 的 CS 明显低于远视组（均 P<0.05）。双眼 qCSF 读数与较低 RS 的单眼读数显著相关（均 P<0.05）。
RS 和 SE 是儿童未经矫正的 qCSF 的主要影响因素。随着 RS/SE 的增加，中空间频率的 CS 显著降低。在低度近视儿童中，中、高空间频率的 CS 明显降低，为儿童视觉功能筛查提供了实用价值。
