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髓外固定与髓内固定治疗稳定型股骨转子间骨折的系统评价和荟萃分析。

Extramedullary versus intramedullary fixation of stable trochanteric femoral fractures: a systematic review and meta-analysis.

机构信息

Trauma Research Unit, Department of Surgery, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

Department of Surgery, Noordwest Ziekenhuisgroep, Alkmaar, The Netherlands.

出版信息

Arch Orthop Trauma Surg. 2023 Aug;143(8):5065-5083. doi: 10.1007/s00402-023-04902-1. Epub 2023 May 2.

Abstract

OBJECTIVE

This systematic review and meta-analysis compared extramedullary fixation and intramedullary fixation for stable two-part trochanteric femoral fractures (AO type 31-A1) with regards to functional outcomes, complications, and surgical outcomes.

METHODS

Embase, Medline, Web of Science, Cochrane Central Register of Controlled Trials, and Google Scholar were searched for randomized controlled trials (RCTs) and observational studies. Effect estimates were pooled across studies using random effects models. Results were presented as weighted risk ratio (RR) or weighted mean difference (MD) with corresponding 95% confidence interval (95% CI).

RESULTS

Five RCTs (397 patients) and 14 observational studies (21,396 patients) were included. No significant differences in functional outcomes, complications, or surgical outcomes were found between extramedullary and intramedullary fixation devices, except for a difference in duration of surgery (MD 14.1 min, CI 5.76-22.33, p < 0.001) and intra-operative blood loss (MD 92.30 mL, CI 13.49-171.12, p = 0.02), favoring intramedullary fixation.

CONCLUSION

Current literature shows no meaningful differences in complications, surgical, or functional outcomes between extramedullary and intramedullary fixation of stable two-part trochanteric femoral fractures. Both treatment options result in good outcomes. This study implicates that, costs should be taken into account when considering implants or comparing fixation methods in future research.

摘要

目的

本系统评价和荟萃分析比较了髓外固定和髓内固定治疗稳定型两部分转子间股骨骨折(AO 31-A1 型)在功能结果、并发症和手术结果方面的差异。

方法

检索了 Embase、Medline、Web of Science、Cochrane 中央对照试验注册库和 Google Scholar 中的随机对照试验(RCT)和观察性研究。使用随机效应模型对研究间的效应估计值进行了汇总。结果以加权风险比(RR)或加权均数差(MD)及其相应的 95%置信区间(95%CI)表示。

结果

纳入了 5 项 RCT(397 例患者)和 14 项观察性研究(21396 例患者)。髓外和髓内固定装置在功能结果、并发症或手术结果方面没有显著差异,除了手术时间(MD 14.1 分钟,CI 5.76-22.33,p<0.001)和术中出血量(MD 92.30 毫升,CI 13.49-171.12,p=0.02)存在差异,髓内固定更有优势。

结论

目前的文献表明,稳定型两部分转子间股骨骨折的髓外和髓内固定在并发症、手术或功能结果方面没有显著差异。两种治疗选择都能取得良好的结果。本研究表明,在未来的研究中,考虑植入物或比较固定方法时,应考虑成本因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a4/10374813/f69b007e3127/402_2023_4902_Fig1_HTML.jpg

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