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头颈部癌症患者接受微血管游离皮瓣手术后的术后恢复:使用镇静剂和机械通气与 ICU 住院时间的关系。

Postoperative recovery among head and neck cancer patients receiving microvascular free flap surgery with implementing nurse-protocolized targeted sedation: relationship of use of sedatives and mechanical ventilation to length of ICU stay.

机构信息

Department of Nursing, Taipei Veterans General Hospital, Taipei, Taiwan.

School of Nursing, National Defense Medical Center, Taipei, Taiwan.

出版信息

Support Care Cancer. 2023 May 3;31(5):317. doi: 10.1007/s00520-023-07730-6.

DOI:10.1007/s00520-023-07730-6
PMID:37133641
Abstract

PURPOSE

Patients receiving microvascular free flap surgery are usually admitted to a high-dependency adult intensive care unit (ICU). Research is limited to investigate postoperative recovery among head and neck cancer patients in the ICU. This study aimed to evaluate a nursing-protocolized targeted sedation on postoperative recovery and to examine the relationship of demographic characteristics, use of sedation, mechanical ventilator to length of ICU stay in patients receiving microvascular free flap surgery for head and neck reconstruction.

METHODS

This retrospective study involves 125 ICU patients at a medical centre in Taiwan. Medical records were reviewed between 1 January 2015 and 31 December 2018 including surgery-related data, medications and sedations used, and ICU-related outcomes.

RESULTS

The mean length of ICU stay was 6.2 days (SD = 2.6), and the mean duration of mechanical ventilation was 4.7 days (SD = 2.3). The daily dosage of sedation used in patients who received microvascular free flap surgery was dramatically reduced since the postoperative day (POD) 7. Over 50% of patients switched to PS + SIMV ventilator mode on POD 4. Duration of sedation used (r = 0.331, p < 0.001), total dosage of sedation (r = 0.901, p < 0.001), clear consciousness (r =  - 0.517, p < 0.001), and duration on mechanical ventilator (r = 0.378, p < 0.001) are correlated with the length of ICU stay.

CONCLUSION

This study provides an understanding of the use of sedation, mechanical ventilator, and length of ICU stay to inform the continued education for clinicians.

摘要

目的

接受微血管游离皮瓣手术的患者通常会被收治在高依赖成人重症监护病房(ICU)。目前的研究仅限于调查 ICU 中头颈部癌症患者的术后恢复情况。本研究旨在评估针对术后恢复的护理协议化靶向镇静,并研究接受头颈部重建微血管游离皮瓣手术的患者中人口统计学特征、镇静使用、机械通气与 ICU 住院时间之间的关系。

方法

这是一项在台湾一家医疗中心进行的回顾性研究,共纳入了 125 名 ICU 患者。研究人员回顾了 2015 年 1 月 1 日至 2018 年 12 月 31 日期间的病历资料,包括手术相关数据、使用的药物和镇静剂以及 ICU 相关结局。

结果

患者 ICU 住院时间的平均长度为 6.2 天(SD=2.6),机械通气的平均持续时间为 4.7 天(SD=2.3)。接受微血管游离皮瓣手术的患者,术后第 7 天开始,镇静药物的日剂量显著减少。超过 50%的患者在术后第 4 天切换至 PS+SIMV 通气模式。镇静使用时间(r=0.331,p<0.001)、镇静总剂量(r=0.901,p<0.001)、意识清醒(r=-0.517,p<0.001)和机械通气时间(r=0.378,p<0.001)与 ICU 住院时间相关。

结论

本研究深入了解了镇静药物、机械通气和 ICU 住院时间的使用情况,为临床医生的继续教育提供了参考。

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Postoperative recovery among head and neck cancer patients receiving microvascular free flap surgery with implementing nurse-protocolized targeted sedation: relationship of use of sedatives and mechanical ventilation to length of ICU stay.头颈部癌症患者接受微血管游离皮瓣手术后的术后恢复:使用镇静剂和机械通气与 ICU 住院时间的关系。
Support Care Cancer. 2023 May 3;31(5):317. doi: 10.1007/s00520-023-07730-6.
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Head and neck surgical oncology.头颈部肿瘤外科学。
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Factors Impacting Discharge Destination Following Head and Neck Microvascular Reconstruction.影响头颈部微血管重建术后出院目的地的因素
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Post-operative Monitoring for Head and Neck Microvascular Reconstruction in the Era of Resident Duty Hour Restrictions: A Retrospective Cohort Study Comparing 2 Monitoring Protocols.
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Impact of preoperative and intraoperative management on outcomes in osteoradionecrosis requiring free flap reconstruction.术前和术中管理对放射性骨坏死需游离皮瓣重建患者结局的影响。
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Management of Flap Failure After Head and Neck Reconstruction: A Systematic Review and Meta-analysis.头颈部重建后皮瓣失败的处理:系统评价和荟萃分析。
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Nurses' Attitudes and Practices Related to Sedation: A National Survey.护士镇静相关态度与实践:全国性调查。
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Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU.成人 ICU 患者疼痛、躁动/镇静、谵妄、活动减少、睡眠障碍预防与管理临床实践指南。
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