Department of Neuroscience and Pharmacology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Department of Neuroscience and Pharmacology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA; Iowa Neuroscience Institute and Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa, Iowa City, IA 52242, USA.
Cell Metab. 2023 May 2;35(5):723-725. doi: 10.1016/j.cmet.2023.04.005.
Dieting often fails in the long run becuase of an ever-growing urge to eat. In this issue of Cell Metabolism, Grzelka et al. unveil a brain circuit that is potentiated during caloric restriction and incites rebound increases in food consumption and body weight.
节食从长期来看往往会失败,因为人们总有强烈的进食欲望。在本期《细胞代谢》杂志中,Grzelka 等人揭示了一条在热量限制期间被增强的大脑回路,它会激起食物摄入量和体重的反弹性增加。