Critcher Shelby, Parmelee Patricia, Freeborn Todd J
Department of Electrical and Computer EngineeringThe University of Alabama Tuscaloosa AL 35487 USA.
Department of PsychologyThe University of Alabama Tuscaloosa AL 35487 USA.
IEEE Open J Eng Med Biol. 2023 Mar 13;4:1-10. doi: 10.1109/OJEMB.2023.3256181. eCollection 2023.
The drastic increase in the aging population has increased the prevalence of osteoarthritis in the United States. The ability to monitor symptoms of osteoarthritis (such as pain) within a free-living environment could improve understanding of each person's experiences with this disease and provide opportunities to personalize treatments specific to each person and their experience. In this work, localized knee tissue bioimpedance and self-reports of knee pain were collected from older adults ([Formula: see text]) with and without knee osteoarthritis over 7 days of free-living to evaluate if knee tissue bioimpedance is associated with persons' knee pain experience. Within the group of persons' with knee osteoarthritis increases in 128 kHz per-length resistance and decreases in 40 kHz per-length reactance were associated with increased probability of persons having active knee pain ([Formula: see text] and [Formula: see text]).
美国老龄化人口的急剧增加使得骨关节炎的患病率上升。在自由生活环境中监测骨关节炎症状（如疼痛）的能力，有助于加深对每个人患这种疾病经历的了解，并为根据个人及其经历进行个性化治疗提供机会。在这项研究中，从患有和未患有膝关节骨关节炎的老年人（[公式：见正文]）中收集了7天自由生活期间的局部膝关节组织生物阻抗和膝关节疼痛的自我报告，以评估膝关节组织生物阻抗是否与个体的膝关节疼痛经历相关。在患有膝关节骨关节炎的人群中，128kHz每长度电阻的增加和40kHz每长度电抗的降低与膝关节疼痛发作概率的增加相关（[公式：见正文]和[公式：见正文]）。
