Institut Pasteur, Université Paris Cité, Emerging Diseases Epidemiology Unit, Paris, France.
Center for Interdisciplinary Research in Biology, Ecology and Evolution of Health team (Collège de France, CNRS/UMR 7241, Inserm U1050), Paris, France.
Euro Surveill. 2023 May;28(18). doi: 10.2807/1560-7917.ES.2023.28.18.2200781.
BackgroundFollowing the SARS-CoV-2 Omicron variant spread, the use of unsupervised antigenic rapid diagnostic tests (self-tests) increased.AimThis study aimed to measure self-test uptake and factors associated with self-testing.MethodsIn this cross-sectional study from 20 January to 2 May 2022, the case series from a case-control study on factors associated with SARS-CoV-2 infection were used to analyse self-testing habits in France. A multivariable quasi-Poisson regression was used to explore the variables associated with self-testing among symptomatic cases who were not contacts of another infected individual. The control series from the same study was used as a proxy for the self-test background rate in the non-infected population of France.ResultsDuring the study period, 179,165 cases who tested positive through supervised tests were recruited. Of these, 64.7% had performed a self-test in the 3 days preceding this supervised test, of which 79,038 (68.2%) were positive. The most frequently reported reason for self-testing was the presence of symptoms (64.6%). Among symptomatic cases who were not aware of being contacts of another case, self-testing was positively associated with being female, higher education, household size, being a teacher and negatively associated with older age, not French by birth, healthcare-related work and immunosuppression. Among the control series, 12% self-tested during the 8 days preceding questionnaire filling, with temporal heterogeneity.ConclusionThe analysis showed high self-test uptake in France with some inequalities which must be addressed through education and facilitated access (cost and availability) for making it a more efficient epidemic control tool.
随着 SARS-CoV-2 奥密克戎变异株的传播,非监督抗原快速诊断检测(自测)的使用有所增加。
本研究旨在测量自测的采用情况以及与自测相关的因素。
在这项 2022 年 1 月 20 日至 5 月 2 日进行的横断面研究中,使用与 SARS-CoV-2 感染相关因素的病例对照研究的病例系列来分析法国的自测习惯。使用多变量拟泊松回归来探讨在未接触其他感染者的症状病例中与自测相关的变量。同一研究的对照系列被用作法国未感染人群中自测背景率的替代指标。
在研究期间,共招募了 179165 例通过监督检测呈阳性的病例。其中,64.7%的人在进行监督检测的前 3 天内进行了自测,其中 79038 人(68.2%)呈阳性。报告最多的自测原因是出现症状(64.6%)。在不知道自己是另一个病例接触者的症状病例中,自测与女性、较高的教育程度、家庭规模、教师职业有关,与年龄较大、非法国出生、与医疗保健相关的工作和免疫抑制呈负相关。在对照系列中,12%的人在填写问卷前的 8 天内进行了自测,存在时间异质性。
分析表明,法国的自测采用率很高,但存在一些不平等现象,必须通过教育和促进(成本和可用性)来解决,使其成为更有效的疫情控制工具。