Associate Laboratory i4HB - Institute for Health and Bioeconomy, School of Science and Technology, NOVA University Lisbon, Caparica, Portugal.
UCIBIO - Applied Molecular Biosciences Unit, Department of Chemistry, Faculty of Sciences and Technology, School of Science and Technology, NOVA University Lisbon, Caparica, Portugal.
Int Microbiol. 2023 Nov;26(4):1123-1130. doi: 10.1007/s10123-023-00367-9. Epub 2023 May 4.
Microalgae are photosynthetic organisms that can produce biomolecules with industrial interest, including exopolysaccharides (EPS). Due to their structural and compositional diversity, microalgae EPS present interesting properties that can be considered in cosmetic and/or therapeutic areas. Seven microalgae strains from three different lineages, namely Dinophyceae (phylum Miozoa), Haptophyta, and Chlorophyta, were investigated as EPS producers. All strains were found to be EPS producers, though the highest EPS yield was obtained for Tisochrysis lutea, followed by Heterocapsa sp. (126.8 and 75.8 mg L, respectively). Upon assessment of the polymers' chemical composition, significant contents of unusual sugars, including fucose, rhamnose, and ribose, were found. Heterocapsa sp. EPS stood out due to its high content of fucose (40.9 mol%), a sugar known to confer biological properties to polysaccharides. The presence of sulfate groups (10.6-33.5 wt%) was also noticed in the EPS produced by all microalgae strains, thus contributing to the possibility that these EPS might have biological activities worth exploring.
微藻是具有光合作用的生物体，能够产生具有工业兴趣的生物分子，包括胞外多糖（EPS）。由于其结构和组成的多样性，微藻 EPS 具有有趣的性质，可以考虑在化妆品和/或治疗领域应用。本研究调查了来自三个不同谱系的七种微藻菌株，即甲藻（原生动物门）、金藻和绿藻，以确定它们是否为 EPS 产生菌。所有菌株均被发现为 EPS 产生菌，尽管小球藻（T. lutea）和异胶藻（Heterocapsa sp.）的 EPS 产量最高（分别为 126.8 和 75.8 mg/L）。在评估聚合物的化学组成时，发现了包括岩藻糖、鼠李糖和核糖在内的不常见糖的大量存在。异胶藻 EPS 因其高含量的岩藻糖（40.9 摩尔%）而引人注目，这种糖已知能赋予多糖生物特性。所有微藻菌株产生的 EPS 中还存在硫酸基团（10.6-33.5wt%），这也使得这些 EPS 可能具有值得探索的生物活性成为可能。
