[Changing of organ distribution of radioactive yttrium in rats by varying amounts of carrier].

There is little change in the organ distribution of yttrium citrate complex after addition of 0.01 mg/kg BW as carrier. Adding increasing amounts of inactive yttrium up to 1 mg/kg BW caused a considerable reduction in bone uptake and an increasing accumulation in the liver and spleen by transformation to colloid. Uptake in the lung indicates formation of macro-particles. The transformation into colloid can be varied by changing the citrate concentration. The 90Y-citrate complex for therapy should be used either without or with very little carrier of inactive yttrium.