Singer C R, Boulton-Jones J M
Postgrad Med J. 1986 Mar;62(725):213-7. doi: 10.1136/pgmj.62.725.213.
Nephrotic syndrome associated with extra-renal malignancy shows a characteristic pattern: carcinoma is most frequently associated with membranous glomerulonephritis and Hodgkin's disease with minimal change nephropathy. We report a patient with minimal change nephropathy in association with anaplastic carcinoma of the bronchus. Strong temporal evidence of a causal relationship is presented. The dissociation in the response of the two conditions to treatment of the tumour after relapse may be evidence of an indirect pathogenesis.
癌最常与膜性肾小球肾炎相关,而霍奇金病则与微小病变性肾病相关。我们报告一例患有微小病变性肾病并伴有支气管间变性癌的患者。文中提供了强有力的时间性证据以证明因果关系。复发后两种病症对肿瘤治疗反应的分离现象可能是间接发病机制的证据。