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二极管激光治疗新冠后综合征患者味觉丧失:一项随机临床试验。

Diode laser in management of loss of taste sensation in patients with post-COVID syndrome: a randomized clinical trial.

机构信息

Oral & Maxillofacial Surgery Department, Faculty of Dentistry, Fayoum University, Fayoum, Egypt.

Department of Maxillofacial Surgery, Al-Alamin Hospital, Ministry of Health, Al-Alamin, Egypt.

出版信息

BMC Oral Health. 2023 May 6;23(1):263. doi: 10.1186/s12903-023-02952-w.

Abstract

OBJECTIVE

Loss of taste (ageusia) is a symptom observed following recovery from COVID-19 infection. The loss of taste and smell sensation may negatively affect patients' quality of life (QoL). The present study aimed to evaluate the effectiveness of the Diode Laser in managing loss of taste sensation in patients with post-COVID syndrome versus the placebo.

MATERIAL AND METHOD

The study sample was 36 patients who complained of persistent loss of taste sensation following COVID-19. The patients were randomly assigned to one of the two groups according to the received treatment: Group I (laser treatment) and Group II (light treatment), with each patient receiving a diode laser treatment or placebo from the same operator. Taste sensation was subjectively measured after treatment for four weeks.

RESULTS

The results demonstrated a significant difference between both groups regarding taste restoration after one month (p = 0.041), with Group II having a significantly higher percentage of cases 7 (38.9%) with partial taste restoration. In contrast, a significantly higher proportion of Group I 17 cases (94.4%) had complete taste restoration (p < 0.001).

CONCLUSION

The present study concluded that using a Diode laser 810 nm aided in a more rapid recovery from loss of taste dysfunction.

摘要

目的

味觉丧失(味觉障碍)是 COVID-19 感染后恢复的一种症状。味觉和嗅觉丧失可能会对患者的生活质量(QoL)产生负面影响。本研究旨在评估二极管激光在治疗 COVID-19 后综合征患者味觉丧失方面的有效性,与安慰剂相比。

材料和方法

研究样本为 36 名抱怨 COVID-19 后持续味觉丧失的患者。根据所接受的治疗,患者被随机分配到两组之一:组 I(激光治疗)和组 II(光治疗),每个患者由同一位操作者接受二极管激光治疗或安慰剂治疗。治疗四周后,对味觉进行主观测量。

结果

结果显示,两组在一个月后味觉恢复方面存在显著差异(p=0.041),组 II 中有 7 例(38.9%)味觉部分恢复的比例明显更高。相比之下,组 I 中有 17 例(94.4%)的患者味觉完全恢复的比例明显更高(p<0.001)。

结论

本研究得出结论,使用 810nm 二极管激光有助于更快地恢复味觉功能障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/347e/10164320/dd9ef961d490/12903_2023_2952_Fig1_HTML.jpg

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