Saraswat Shelesh Krishna, Seemaladinne Ramanjaneyulu, Abdullah Media Noori, Zaini Halim, Ahmad Nabeel, Ahmad Nafis, Vessally Esmail
Department of ECE, Gla University Mathura India.
Department of Chemistry and Bio Chemistry, Lamar University Beaumont Texas USA.
RSC Adv. 2023 May 3;13(20):13642-13654. doi: 10.1039/d3ra01791e. eCollection 2023 May 2.
Aryl fluorosulfates are versatile building blocks in organic synthesis and have gained increasing attention in SuFEx (Sulfur Fluoride Exchange) click chemistry. They are easily and conveniently prepared from phenols using sulfuryl fluoride SOF as a low-cost sulfonyl fluoride provider. Recently, they served as less toxic and more atom economical alternatives to triflates in an impressive number of carbon-carbon and carbon-heteroatom cross-coupling reactions. In this review, we summarize the current advances and developments in applying aryl fluorosulfates as electrophilic partners in cross-coupling reactions.
芳基氟硫酸盐是有机合成中用途广泛的结构单元，并且在硫氟交换（SuFEx）点击化学中受到越来越多的关注。它们可以使用廉价的磺酰氟供应源——氟化硫酰（SOF），由苯酚轻松便捷地制备得到。最近，在众多的碳-碳和碳-杂原子交叉偶联反应中，它们作为毒性较低且原子经济性更高的三氟甲磺酸盐替代品发挥了作用。在本综述中，我们总结了将芳基氟硫酸盐用作交叉偶联反应中亲电试剂的当前进展与发展情况。
