芳基肼：交叉偶联反应中新型且通用的亲电试剂

Hosseinian Akram, Mohammadi Robab, Ahmadi Sheida, Monfared Aazam, Rahmani Zahra

School of Engineering Science, College of Engineering, University of Tehran P. O. Box 11365-4563 Tehran Iran

Department of Chemistry, Payame Noor University P. O. Box 19395-3697 Tehran Iran.

RSC Adv. 2018 Oct 1;8(59):33828-33844. doi: 10.1039/c8ra06423g. eCollection 2018 Sep 28.

Arylhydrazines are extremely valuable compounds in organic chemistry that are widely used for the synthesis of a variety of biologically active molecules such as indoles, indazoles, pyrazoles, aryltriazoles, β-lactams and quinazolines. These compounds have also been widely utilized as arylation agents in oxidative cross-coupling reactions. In this review, we will highlight the most important explorations and developments in the carbon-carbon and carbon-heteroatom (nitrogen, phosphorus, sulfur, and selenium) cross-coupling of arylhydrazines. The literature has been surveyed from 2001 to June 2018.

芳基肼是有机化学中极具价值的化合物，广泛用于合成多种生物活性分子，如吲哚、吲唑、吡唑、芳基三唑、β-内酰胺和喹唑啉。这些化合物也被广泛用作氧化交叉偶联反应中的芳基化试剂。在本综述中，我们将重点介绍芳基肼在碳-碳和碳-杂原子（氮、磷、硫和硒）交叉偶联方面最重要的探索和进展。我们对2001年至2018年6月的文献进行了调研。