Graduate School, Hebei Medical University, Shijiazhuang, Hebei, China.
Department of Endocrinology, Hebei General Hospital, Shijiazhuang, Hebei, China.
Front Endocrinol (Lausanne). 2023 Apr 19;14:1136048. doi: 10.3389/fendo.2023.1136048. eCollection 2023.
Non-fasting lipid assessment can help predict cardiovascular disease risks and is linked to multiple diseases, particularly diabetes. The significance of non-fasting lipid levels in routine screening and postprandial lipid tests for potential dyslipidemia has not been conclusively determined. Various new lipid-lowering strategies have been developed to improve non-fasting dyslipidemia. Therefore, analysis of scientific outputs over the past decade is essential to reveal trends, hotspots, and frontier areas for future research in this field.
The Science Citation Index Expanded in the Web of Science Core Collection database was searched for publications related to non-fasting lipid research from 2012 to 2022. The regional distributions, authors, disciplines, journals, references, and keywords of the studies were analyzed using the bibliometric software VOSviewer and CiteSpace.
A total of 4160 articles and reviews that met the inclusion criteria were included in this study. The output trend was established to be stable and the number of citation indices has been persistently increasing. A total of 104 countries/regions, 4668 organizations, and 20782 authors were involved in this research area. In terms of country, the United States had the largest number of publications (979). The University of Copenhagen was the most productive institution, publishing 148 papers. Professor Børge G Nordestgaard has made the most significant contribution to this field. was the most productive journal while the was the highest co-cited journal. Analysis of co-cited references indicated that lipid-lowering strategies, statin therapy, high-fat meals, insulin resistance, physical exercise, and fructose were hotspots. Analysis of co-cited keywords revealed that apolipoprotein B, especially apolipoprotein B48, is becoming a key research focus. The keywords "gut microbiota" and "meal timing" were the most extensively studied.
The causal relationship between non-fasting dyslipidemia and diseases is currently being explored and the standards for non-fasting or postprandial lipid assessment are continuously being updated. Among the hotspots, lipid-lowering strategies are a potential research direction. Apolipoprotein B48, gut microbiota, and chrononutrition are the research frontiers. This initial bibliometric analysis of non-fasting lipids will enable researchers to monitor swift transformations and recognize novel concepts for upcoming research.
非空腹血脂评估有助于预测心血管疾病风险，与多种疾病相关，尤其是糖尿病。非空腹血脂在常规筛查和餐后血脂检测中对潜在血脂异常的意义尚未得到明确确定。已经开发了各种新的降脂策略来改善非空腹血脂异常。因此，分析过去十年的科学产出对于揭示该领域未来研究的趋势、热点和前沿领域至关重要。
在 Web of Science 核心合集数据库的科学引文索引扩展版中搜索了 2012 年至 2022 年与非空腹血脂研究相关的出版物。使用文献计量学软件 VOSviewer 和 CiteSpace 分析了研究的地区分布、作者、学科、期刊、参考文献和关键词。
共纳入符合纳入标准的 4160 篇文章和综述。建立了输出趋势，表明数量稳定且引文指数持续增加。共有 104 个国家/地区、4668 个组织和 20782 名作者参与了该研究领域。就国家而言，美国发表的文章最多（979 篇）。哥本哈根大学是最具生产力的机构，发表了 148 篇论文。Børge G Nordestgaard 教授对该领域的贡献最大。是发表文章最多的期刊，而 是被引频次最高的期刊。共引参考文献分析表明，降脂策略、他汀类药物治疗、高脂餐、胰岛素抵抗、体育锻炼和果糖是热点。共引关键词分析表明载脂蛋白 B，尤其是载脂蛋白 B48，正在成为一个关键的研究重点。“肠道微生物群”和“用餐时间”是研究最多的关键词。
目前正在探索非空腹血脂异常与疾病之间的因果关系，并且非空腹或餐后血脂评估的标准在不断更新。在热点中，降脂策略是一个潜在的研究方向。载脂蛋白 B48、肠道微生物群和时间营养是研究前沿。对非空腹血脂的初步文献计量学分析将使研究人员能够监测迅速的转变，并识别即将到来的研究中的新概念。
