Reigel F, Burkhardt F, Schilt U
Schweiz Med Wochenschr. 1986 Apr 19;116(16):510-3.
HBV markers were tested in sera of patients with various clinical and serological states of HBV infection, including patients with delta-infection, and were compared to the detection of HBV-DNA in the sera by hybridization. The results show that high levels of HBV-DNA (much greater than 100 pg/0.1 ml) are mainly found in sera of patients with chronic hepatitis or in early sera of HBs antigen carriers, while 17 of 20 patients with undetectable or trace amounts of DNA in early sera exhibited a self-limiting hepatitis infection. This test system could be prognostic value.
在各种临床和血清学状态的乙肝病毒（HBV）感染患者的血清中检测HBV标志物，包括丁型肝炎感染患者，并通过杂交将其与血清中HBV-DNA的检测结果进行比较。结果显示，高浓度的HBV-DNA（远高于100 pg/0.1 ml）主要见于慢性肝炎患者的血清或乙肝表面抗原携带者的早期血清中，而早期血清中检测不到或仅有微量DNA的20例患者中有17例表现为自限性肝炎感染。该检测系统可能具有预后价值。
