Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Department of Reconstructive Orthopaedics, Karolinska University Hospital, Stockholm, Sweden.
PLoS One. 2023 May 8;18(5):e0285246. doi: 10.1371/journal.pone.0285246. eCollection 2023.
Idiopathic scoliosis is the most common spinal deformity in children. Treatment strategies aim to halt progression of the curve. Mild scoliosis is in many cases observed or, in some cases, treated with scoliosis-specific exercises. More severe curves are treated mainly with a brace. The aim of this study is to investigate the effectiveness of scoliosis-specific exercises compared to observation in adolescents with mild idiopathic scoliosis.
Subjects. Previously untreated and skeletally immature children aged 9-15 years of age with idiopathic scoliosis (curve magnitude Cobb 15-24 degrees) will be included. A total of 90 subjects will be included to receive one of two possible interventions. Interventions. Both groups will receive a physical activity prescription according to the World Health Organization recommendations. The intervention group will receive an additional active self-correction treatment strategy for curve correction and will have outpatient sessions once every two weeks for the first three months. They will be prescribed to do the exercises at least three times per week. The intervention will be performed until skeletal maturity or progression of the curve. Outcome. The subjects will participate in the study until curve progression or until skeletal maturity (defined as less than 1 cm growth for six months). The primary outcome variable is failure of treatment, defined as progression of the Cobb angle more than 6 degrees on two consecutive x-rays compared to the baseline x-ray. Secondary outcome measures include patient-reported outcomes, clinical characteristics (i.e. angle of trunk rotation and trunk asymmetry) and number requiring brace treatment. Clinical follow-ups will be performed every six months and radiographs will be taken annually.
This study will compare effectiveness of an active self-corrective exercise strategy in mild idiopathic scoliosis with observation in terms of halting curve progression.
特发性脊柱侧凸是儿童中最常见的脊柱畸形。治疗策略旨在阻止曲线的进展。在许多情况下，轻度脊柱侧凸是观察到的，或者在某些情况下，使用脊柱侧凸特异性运动来治疗。更严重的曲线主要用支具治疗。本研究旨在比较特发性脊柱侧凸轻度青少年中脊柱侧凸特异性运动与观察的疗效。
受试者。将纳入未经治疗且骨骼未成熟的特发性脊柱侧凸（曲线幅度 Cobb 15-24 度）的 9-15 岁儿童。总共将纳入 90 名受试者，接受两种可能干预措施之一。干预。两组均按世界卫生组织建议进行体育活动处方。干预组将接受额外的主动自我矫正治疗策略进行曲线矫正，并在前三个月每两周进行一次门诊治疗。规定他们每周至少做三次运动。干预将持续到骨骼成熟或曲线进展。结果。受试者将参加研究，直到曲线进展或骨骼成熟（定义为六个月内生长少于 1 厘米）。主要结局变量是治疗失败，定义为与基线 X 光片相比，连续两次 X 光片上 Cobb 角增加超过 6 度。次要结局指标包括患者报告的结果、临床特征（即躯干旋转角度和躯干不对称）以及需要支具治疗的人数。临床随访每六个月进行一次，每年进行 X 光检查。
本研究将比较主动自我矫正运动策略在轻度特发性脊柱侧凸中的有效性与观察在阻止曲线进展方面的效果。
