From the Department of Neurosciences (A.N., K.M., J.N.L.), University of California San Diego; Office of the Coroner Ada County (C.D.L.), Boise, ID; and Department of Neurology (R.A.), Keck School of Medicine of USC, Los Angeles, CA.
Neurology. 2023 Aug 22;101(8):e845-e851. doi: 10.1212/WNL.0000000000207386. Epub 2023 May 8.
A wide variety of diseases present with intracranial lesions. In this case report, a 67-year-old man initially presented to an outside hospital with nausea, headache, and ataxia and was found to have multiple intracranial lesions. Diagnostic workup was ultimately unrevealing, and his condition improved after a course of steroids and antibiotics. Unfortunately, symptoms returned 3 months later. MRI of the brain revealed progression of his intracranial lesions. This case highlights a diagnostic approach and general management strategy for patients presenting with undifferentiated intracranial pathology. A final diagnosis is ultimately reached and raises further discussion.
多种疾病表现为颅内病变。在本病例报告中,一名 67 岁男性最初因恶心、头痛和共济失调就诊于外院,并发现存在多处颅内病变。诊断性检查最终未能明确病因,经类固醇和抗生素治疗后病情有所改善。然而,3 个月后症状再次出现。脑部 MRI 显示颅内病变进展。本病例强调了对表现为未分化颅内病变患者的诊断方法和一般治疗策略。最终诊断明确,并引发了进一步的讨论。