Marchuk G I, Berbentsova E P
Ter Arkh. 1986;58(3):63-70.
The authors describe the results of application during 6 months of a quantitative method involving the use of the clinical and laboratory indicators of the disease gravity in routine medical work, which included correction of the therapeutic tactics as regards the immunological characteristics in 668 patients with acute pneumonia, 1100 with chronic bronchitis, and 120 with bronchial asthma. The use of the indicators of the disease gravity made it possible to objectively evaluate the gravity and the time-course of the diseases under consideration, to decide on the etiological treatment, to control the treatment efficacy and make necessary corrections, to specify the time of administration and withdrawal of biological stimulation, as well as to define the time of convalescence or remission. The authors have developed indications and specified contraindications as to the use of passive immunization and biological (immunocorrective) stimulation in the management of acute pneumonia.
作者描述了一种定量方法在6个月应用期间的结果，该方法涉及在日常医疗工作中使用疾病严重程度的临床和实验室指标，其中包括针对668例急性肺炎患者、1100例慢性支气管炎患者和120例支气管哮喘患者的免疫特征对治疗策略进行调整。使用疾病严重程度指标能够客观评估所研究疾病的严重程度和病程，决定病因治疗，控制治疗效果并进行必要的调整，明确生物刺激的给药和停药时间，以及确定康复或缓解时间。作者制定了关于在急性肺炎治疗中使用被动免疫和生物（免疫纠正）刺激的适应证和明确的禁忌证。
