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铁逆向信号机制和光合生物铁摄取调控的研究进展。

Advances in Iron Retrograde Signaling Mechanisms and Uptake Regulation in Photosynthetic Organisms.

机构信息

Centro de Estudios Fotosintéticos y Bioquímicos (CEFOBI-CONICET), Universidad Nacional de Rosario, Rosario, Argentina.

出版信息

Methods Mol Biol. 2023;2665:121-145. doi: 10.1007/978-1-0716-3183-6_11.

DOI:10.1007/978-1-0716-3183-6_11
PMID:37166598
Abstract

Iron (Fe) is an essential metal for the growth and development of different organisms, including plants and algae. This metal participates in different biological processes, among which are cellular respiration and photosynthesis. Fe is found associated with heme groups and as part of inorganic Fe-S groups as cofactors of numerous cellular proteins. Although Fe is abundant in soils, it is often not bioavailable due to soil pH. For this reason, photosynthetic organisms have developed different strategies for the uptake, the sensing of Fe intracellular levels but also different mechanisms that maintain and regulate adequate concentrations of this metal in response to physiological needs. This work focuses on discussing recent advances in the characterization of the mechanisms of Fe homeostasis and Fe retrograde signaling in photosynthetic organisms.

摘要

铁(Fe)是包括植物和藻类在内的不同生物体生长和发育所必需的金属。这种金属参与了不同的生物过程,其中包括细胞呼吸和光合作用。Fe 与血红素基团结合,并作为许多细胞蛋白的无机 Fe-S 基团的一部分作为辅因子。尽管 Fe 在土壤中含量丰富,但由于土壤 pH 值,它通常不易被生物利用。出于这个原因,光合生物已经发展出了不同的策略来吸收、感应细胞内 Fe 水平,以及不同的机制来维持和调节这种金属的适当浓度,以响应生理需求。本文重点讨论了在光合生物中 Fe 稳态和 Fe 逆行信号转导机制的特征方面的最新进展。

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Plant Commun. 2023 Jan 9;4(1):100411. doi: 10.1016/j.xplc.2022.100411. Epub 2022 Jul 14.
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ROS production and signalling in chloroplasts: cornerstones and evolving concepts.叶绿体中 ROS 的产生和信号转导:基石和不断发展的概念。
Plant J. 2022 Aug;111(3):642-661. doi: 10.1111/tpj.15856. Epub 2022 Jun 28.
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Recent Advances in the Elucidation of Frataxin Biochemical Function Open Novel Perspectives for the Treatment of Friedreich's Ataxia.
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Front Neurosci. 2022 Mar 2;16:838335. doi: 10.3389/fnins.2022.838335. eCollection 2022.
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PAP/SAL1 retrograde signaling pathway modulates iron deficiency response in alkaline soils.PAP/SAL1 逆行信号通路调节碱性土壤中铁元素缺乏的响应。
Plant Sci. 2021 Mar;304:110808. doi: 10.1016/j.plantsci.2020.110808. Epub 2020 Dec 26.
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All together now: regulation of the iron deficiency response.现在大家一起:调控缺铁反应。
J Exp Bot. 2021 Mar 17;72(6):2045-2055. doi: 10.1093/jxb/erab003.
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Mol Plant. 2020 Apr 6;13(4):634-649. doi: 10.1016/j.molp.2020.01.006. Epub 2020 Jan 18.
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