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附属微生物组。

Accessory microbiomes.

机构信息

European Centre for Environment and Human Health, Environment and Sustainability Institute, University of Exeter, Penryn Campus, TR10 9FE, Penryn, UK.

出版信息

Microbiology (Reading). 2023 May;169(5). doi: 10.1099/mic.0.001332.

Abstract

In microbiome research, considerable effort has been invested in finding core microbiomes, which have been hypothesized to contain the species most important for host function. Much less attention has been paid to microbiome members that are present in only a subset of hosts. Such accessory microbiomes must in large part consist of species that have no effect on fitness, but some will have deleterious effects on fitness (pathogens), and it is also possible that some accessory microbiome members benefit an ecologically distinct subset of hosts. This short paper discusses what we know about accessory microbiomes, specifically by comparing it with the concept of accessory genomes.

摘要

在微生物组研究中,人们投入了大量精力来寻找核心微生物组,这些微生物组被假设包含对宿主功能最重要的物种。然而,人们对仅存在于宿主亚群中的微生物组成员关注较少。这些辅助微生物组在很大程度上必须由对适应性没有影响的物种组成,但也有一些会对适应性产生有害影响(病原体),而且一些辅助微生物组成员也可能使生态上不同的宿主亚群受益。本文简要讨论了我们对辅助微生物组的了解,特别是通过将其与辅助基因组的概念进行比较。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d63/10268833/d2601fadc6f1/mic-169-1332-g001.jpg

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