Patel Shreyan A, Naamo Saba, Li Liping, Jackson Tatianie
Internal Medicine, Edward Via College of Osteopathic Medicine, Blacksburg, USA.
Radiology, Geisinger Medical Center, Danville, USA.
Cureus. 2023 Apr 8;15(4):e37299. doi: 10.7759/cureus.37299. eCollection 2023 Apr.
Diabetic mastopathy is an uncommon, benign breast lesion that is typically seen in patients with type 1 diabetes mellitus (T1DM). The main differential diagnosis for diabetic mastopathy is breast carcinoma, which appears similarly on clinical examination and diagnostic imaging. Although the etiology of diabetic mastopathy is poorly understood, it has been associated with several autoimmune conditions, such as Hashimoto's thyroiditis, systemic lupus erythematosus, and Sjogren's syndrome. Here, we report a case of diabetic mastopathy in a T1DM patient with an associated history of elevated thyroid peroxidase (TPO) and antimitochondrial antibody (AMA) levels, giving further support to the theory of autoimmune etiopathogenesis.
糖尿病性乳腺病是一种罕见的良性乳腺病变，多见于1型糖尿病（T1DM）患者。糖尿病性乳腺病的主要鉴别诊断是乳腺癌，二者在临床检查和诊断性影像学检查中表现相似。尽管糖尿病性乳腺病的病因尚不清楚，但它与几种自身免疫性疾病有关，如桥本甲状腺炎、系统性红斑狼疮和干燥综合征。在此，我们报告1例T1DM患者发生糖尿病性乳腺病，该患者伴有甲状腺过氧化物酶（TPO）和抗线粒体抗体（AMA）水平升高的病史，这进一步支持了自身免疫病因发病机制的理论。
