Soler N G, Khardori R
Lancet. 1984 Jan 28;1(8370):193-5. doi: 10.1016/s0140-6736(84)92114-7.
Fibrous breast lumps were noted in 12 women with longstanding type I diabetes mellitus who had multiple diabetic complications including cheiroarthropathy (11 of 12). 5 of the 12 women also had thyroid microsomal antibodies (greater than 1:1000). The coexistence of cheiroarthropathy and fibrosis of the breasts raises the possibility of a common link related to the connective-tissue abnormalities observed in diabetes. Although autoimmunity may also be a factor, HLA histocompatibility typing did not indicate that these patients formed a distinct subgroup of type I diabetics.
在12名患有长期I型糖尿病且有包括手部关节病（12例中的11例）在内的多种糖尿病并发症的女性中发现了纤维性乳腺肿块。12名女性中有5名还存在甲状腺微粒体抗体（大于1:1000）。手部关节病和乳腺纤维化并存增加了与糖尿病中观察到的结缔组织异常相关的共同联系的可能性。虽然自身免疫也可能是一个因素，但HLA组织相容性分型并未表明这些患者构成I型糖尿病的一个独特亚组。
