一名宫颈癌患者急性难治性放射性膀胱炎的成功植物疗法：病例报告
Successful Phytotherapy for Acute Refractory Radiation Cystitis in a Cervical Cancer Patient: A Case Report.
作者信息
Hoang Ba X, Han B O, Tran Hung Q, Fang William H, Tran Hau D
机构信息
Nimni-Cordoba Tissue Engineering and Drug Discovery Laboratory, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, U.S.A.
Department of Oncology, Phenikaa University, Hanoi, Vietnam.
出版信息
Cancer Diagn Progn. 2023 May 3;3(3):383-386. doi: 10.21873/cdp.10228. eCollection 2023 May-Jun.
BACKGROUND/AIM: Radiation cystitis is a frequent complication that can occur after therapeutic irradiation of pelvic cancers. The current treatment for this condition is complex and often ineffective.
CASE REPORT
We present a clinical case of a 54-year-old patient diagnosed with small cell cervical cancer FIGO stage IIIC who developed grade 2-3 radiation cystitis following post-operational chemoradiation therapy. The patient exhibited increased urinary urgency and frequency, dysuria, and low abdominal pain, which failed to respond to acupuncture and corticosteroid treatments. A course of Ich Nieu Khang phytotherapy tablets, resulted in significant improvement of symptoms within 24 hours of initiation. The symptoms resolved completely within 10 days, and ultrasonography documented a marked decrease in bladder wall thickening and improved bladder evacuation function. The phytotherapy was well-tolerated, and no side-effects were observed during the 60-day treatment period.
CONCLUSION
These findings suggest that phytotherapy may be viable for managing radiation cystitis. However, further controlled clinical trials are needed to confirm the efficacy of Ich Nieu Khang and promote its broader clinical applications.
背景/目的：放射性膀胱炎是盆腔癌症治疗性放疗后常见的并发症。目前针对这种情况的治疗复杂且往往无效。
病例报告
我们报告一例临床病例，一名54岁患者被诊断为国际妇产科联盟（FIGO）IIIC期小细胞宫颈癌，术后放化疗后发生2 - 3级放射性膀胱炎。患者表现出尿急、尿频、尿痛及下腹部疼痛，针灸和皮质类固醇治疗均无效。服用一疗程的Ich Nieu Khang植物疗法片剂后，在开始治疗24小时内症状显著改善。症状在10天内完全缓解，超声检查显示膀胱壁增厚明显减轻，膀胱排空功能改善。植物疗法耐受性良好，在60天治疗期内未观察到副作用。
结论
这些发现表明植物疗法可能对放射性膀胱炎的治疗可行。然而，需要进一步的对照临床试验来证实Ich Nieu Khang的疗效并促进其更广泛的临床应用。
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