Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Eur Psychiatry. 2023 May 12;66(1):e39. doi: 10.1192/j.eurpsy.2023.2407.
Major depressive disorder (MDD) is a leading cause of disability worldwide, and yet delivery of care for this illness is rife with gaps. The COVID-19 pandemic has had far reaching implications for every facet of healthcare, and MDD is no exception. This scoping review aimed to ascertain the impacts of COVID-19 on the delivery of MDD care in Europe, as well as to evaluate any novel MDD care strategies trialled in this period.
We searched the PubMed and PsycINFO databases up to January 2022 with a strategy centred around COVID-19 and MDD. Full texts of eligible studies examining working-age adults and conducted in Europe were evaluated against several criteria. All outcomes were then extracted and a narrative synthesis was constructed to summarise identified themes.
Of 1,744 records identified in our search, 11 articles were eligible for inclusion in the review. In general, these studies reported a decrease in treatment rates, access to care, and perceived access to care during the COVID-19 pandemic. In addition, digital interventions trialled during the pandemic were broadly well-received by users, though their efficacy in improving MDD care was ambiguous.
Despite a limited number of pertinent studies, this scoping review identified a trend of exacerbated treatment gaps in MDD care during the pandemic. Several of our pre-specified gaps, including delays to detection or treatment of depression and rates of follow-up contacts, remained unexplored in the context of COVID-19. This highlights the need for further investigation to obtain a full understanding of the relationship between COVID-19 and MDD care in Europe.
重度抑郁症(MDD)是全球范围内导致残疾的主要原因,但对这种疾病的治疗存在诸多不足。COVID-19 大流行对医疗保健的各个方面都产生了深远的影响,MDD 也不例外。本范围界定审查旨在确定 COVID-19 对欧洲 MDD 治疗的影响,并评估在此期间试用的任何新的 MDD 治疗策略。
我们使用了以 COVID-19 和 MDD 为中心的策略,在 PubMed 和 PsycINFO 数据库中进行了搜索,截止日期为 2022 年 1 月。对符合条件的研究进行了评估,这些研究检查了工作年龄的成年人,并在欧洲进行。然后提取了所有的结果,并进行了叙述性综合以总结确定的主题。
在我们的搜索中确定了 1744 条记录,其中有 11 篇文章符合纳入审查的标准。总体而言,这些研究报告称,在 COVID-19 大流行期间,治疗率、获得治疗的机会和感知到的治疗机会都有所下降。此外,在大流行期间试用的数字干预措施受到用户的广泛好评,但它们在改善 MDD 治疗方面的疗效尚不清楚。
尽管相关研究数量有限,但本范围界定审查确定了在大流行期间 MDD 治疗中治疗差距加剧的趋势。我们预先指定的几个差距,包括抑郁症的发现或治疗延迟以及随访接触的比率,在 COVID-19 背景下仍未得到探索。这突显了需要进一步调查,以充分了解 COVID-19 与欧洲 MDD 治疗之间的关系。