一级多学科护理医院住院患者的抗生素使用模式
Pattern of Antibiotic Use among Hospitalized Patients at a Level One Multidisciplinary Care Hospital.
作者信息
Hodoșan Viviana, Daina Lucia Georgeta, Zaha Dana Carmen, Cotrău Petru, Vladu Adriana, Dorobanțu Florica Ramona, Negrău Marcel Ovidiu, Babeș Elena Emilia, Babeș Victor Vlad, Daina Cristian Marius
机构信息
Faculty of Medicine and Pharmacy, Doctoral School of Biomedical Sciences, University of Oradea, 1st University Street, 410087 Oradea, Romania.
Psycho-Neurosciences and Recovery Department, Faculty of Medicine and Pharmacy, University of Oradea, 1st University Street, 410087 Oradea, Romania.
出版信息
Healthcare (Basel). 2023 May 3;11(9):1302. doi: 10.3390/healthcare11091302.
BACKGROUND
Antimicrobial resistance is one of the world's most serious health issues. Antibiotic resistance, excessive drug expense, and an increased risk of adverse reactions are all common outcomes of incorrect antibiotic prescribing. The goal of this study was to evaluate the prevalence of antibiotic prescriptions for inpatients to find areas for improvement.
METHODS
A retrospective study at Emergency Clinical County Hospital of Oradea, Romania was performed for five years between 2017 and 2021. Data was collected using medical records of the patients and reports from the pharmacy. Antibiotic consumption was expressed as DDD/100 BD according to the World Health Organization (WHO) by antibiotics, classes, and AWaRe classification.
RESULTS
The prevalence of antibiotic prescription was 53.8% during five years evaluated with a significant increase in 2021. A total of 13,677.42 DDD/100 BD antibiotics were prescribed, especially for surgical and medical prophylaxes. The most prescribed antibiotics were ceftriaxone, followed by metronidazole, and cefuroxime but there were some differences between years and wards. The most frequent antibiotic classes prescribed were cephalosporins (43.73%). The use of Watch Group antibiotics was high in all wards (59.69%).
CONCLUSIONS
The prevalence of antibiotic use was high with cephalosporins being the most prescribed antibiotics. As a result, interventions are required.
背景
抗菌药物耐药性是全球最严重的健康问题之一。抗生素耐药性、药物费用过高以及不良反应风险增加都是抗生素处方不当的常见后果。本研究的目的是评估住院患者抗生素处方的流行情况，以找出需要改进的方面。
方法
对罗马尼亚奥拉迪亚市急诊临床县医院进行了一项回顾性研究，研究时间为2017年至2021年的五年间。通过患者病历和药房报告收集数据。根据世界卫生组织（WHO）的标准，按抗生素种类、类别和AWaRe分类法，将抗生素消耗量表示为DDD/100BD。
结果
在评估的五年中，抗生素处方的流行率为53.8%，2021年有显著增加。共开具了13677.42 DDD/100BD的抗生素，主要用于手术和医疗预防。最常开具的抗生素是头孢曲松，其次是甲硝唑和头孢呋辛，但不同年份和病房之间存在一些差异。最常开具的抗生素类别是头孢菌素类（43.73%）。所有病房中观察类抗生素的使用比例都很高（59.69%）。
结论
抗生素使用的流行率很高，头孢菌素类是最常开具的抗生素。因此，需要采取干预措施。
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