National Immunisation Office, Unit 8-9 Manor Street Business Park, Manor Street, Dublin 7, Ireland; Health Protection Surveillance Centre, 25-27 Middle Gardiner Street, Dublin 1, Ireland.
Health Protection Surveillance Centre, 25-27 Middle Gardiner Street, Dublin 1, Ireland; European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden; Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary.
Vaccine. 2023 Jun 7;41(25):3740-3754. doi: 10.1016/j.vaccine.2023.05.004. Epub 2023 May 13.
Vaccine hesitancy is complex and multifactorial and a threat to global health. Uptake of some recommended childhood immunisations in Ireland remains below World Health Organisation targets. The aim of this study was to determine factors associated with vaccine uptake in Ireland.
A cross-sectional, national survey of parental attitudes towards childhood vaccination for children aged 0 to 48 months was conducted between June and August 2021 (N = 855). A descriptive analysis of questionnaire responses was conducted. Univariate and multivariable logistic regression models were constructed to identify the association of demographic parental characteristics and parental vaccine attitude scores with a delay in or lack of parental vaccine acceptance.
There was a strongly positive sentiment towards childhood vaccinations. Self-reported uptake of recommended vaccines was 96.1 % with a strong belief in the importance (94.4 %) and safety (89.2 %) of vaccines. Trust in official vaccine information sources was high; 91.5 % and 89.2 % reported trust in the vaccine information provided by healthcare professionals and the Health Service Executive (HSE) respectively. The most commonly identified reasons for missed vaccines were concerns about safety and vaccine side effects. In multivariable regression analysis, parental trust in official vaccine information sources was a significant predictor of vaccine acceptance. For every one unit increase in the median parental trust in official vaccine information score, the odds of a parent having reduced vaccine acceptance decreased significantly (aOR 0.27 95 % CI 0.16, 0.46, p < 0.001).
Understanding parental attitudes towards vaccination will inform the development of evidence-informed, targeted interventions to increase childhood immunisation uptake. Vaccine information for parents should focus on vaccine safety and public health action should be taken to build trust and engage communities in order to increase and sustain the uptake of childhood vaccines delivered as part of the national childhood primary immunisation programme in Ireland.
疫苗犹豫是复杂的、多因素的，也是对全球健康的威胁。爱尔兰推荐的一些儿童免疫接种的接种率仍低于世界卫生组织的目标。本研究的目的是确定与爱尔兰疫苗接种率相关的因素。
2021 年 6 月至 8 月期间，对 0 至 48 个月龄儿童的父母进行了一项关于儿童疫苗接种态度的横断面、全国性调查（N=855）。对问卷回答进行描述性分析。构建单变量和多变量逻辑回归模型，以确定父母特征和父母疫苗态度评分与延迟或拒绝父母疫苗接种之间的关联。
对儿童疫苗接种有强烈的积极态度。自我报告的推荐疫苗接种率为 96.1%，对疫苗的重要性（94.4%）和安全性（89.2%）有强烈的信念。对官方疫苗信息来源的信任度很高；分别有 91.5%和 89.2%的人报告信任医疗保健专业人员和卫生服务执行局（HSE）提供的疫苗信息。错过疫苗接种的最常见原因是对安全性和疫苗副作用的担忧。在多变量回归分析中，父母对官方疫苗信息来源的信任是疫苗接种接受度的一个显著预测因素。父母对官方疫苗信息来源的信任每增加一个单位，父母减少疫苗接受度的可能性就会显著降低（比值比 0.27，95%置信区间 0.16，0.46，p<0.001）。
了解父母对疫苗接种的态度将为制定以证据为基础的、有针对性的干预措施提供信息，以提高儿童免疫接种率。应向父母提供疫苗信息，重点关注疫苗安全性，并应采取公共卫生行动，建立信任，让社区参与，以增加和维持爱尔兰国家儿童初级免疫接种计划中提供的儿童疫苗接种率。
