Schumacher H R, Sieck M S, Rothfuss S, Clayburne G M, Baumgarten D F, Mochan B S, Kant J A
Arthritis Rheum. 1986 Jun;29(6):770-4. doi: 10.1002/art.1780290610.
Aliquots from 30 synovial fluids were submitted to 4 laboratories for comparison of leukocyte counts and differential cell counts, and to 3 laboratories for a search for and identification of crystals. Leukocyte counts showed only fair correlation (coefficients of 0.76-0.80) with the reference laboratory. In synovial fluid from 4 patients, there was sufficient difference in leukocyte counts to cause the fluids to be erroneously classified as either "inflammatory" or "noninflammatory". In 12 of 24 fluid specimens examined, percentages of neutrophils fell outside the 95% confidence limits of the value determined by the reference laboratory. In 7 of the 11 patients with crystals reported, discrepancies were found between the reports from 1 or more laboratories. More attention to quality control of synovial fluid analyses is important.
从30份滑液中取出的等分试样被送往4个实验室进行白细胞计数和细胞分类计数比较，并送往3个实验室进行晶体的查找和鉴定。白细胞计数与参考实验室的结果仅显示出中等程度的相关性（系数为0.76 - 0.80）。在4名患者的滑液中，白细胞计数存在足够差异，导致这些滑液被错误地归类为“炎症性”或“非炎症性”。在24份检测的液体标本中，有12份中性粒细胞百分比超出了参考实验室测定值的95%置信区间。在报告有晶体的11名患者中，有7名患者的报告在1个或多个实验室之间存在差异。更加重视滑液分析的质量控制很重要。
