与酒精和双硫仑相关的难治性高动力性休克

Refractory hyperdynamic shock associated with alcohol and disulfiram.

作者信息

Motte S, Vincent J L, Gillet J B, Deguate J P, Kahn R J

出版信息

Am J Emerg Med. 1986 Jul;4(4):323-5. doi: 10.1016/0735-6757(86)90301-3.

Abstract

After massive alcohol intake, a patient under disulfiram therapy developed a severe cardiovascular collapse unresponsive to dopamine but successfully reversed with norepinephrine. Resistance to dopamine could be related to norepinephrine depletion caused by disulfiram. Norepinephrine could, therefore, represent the treatment of choice of these life-threatening conditions.

摘要

在大量饮酒后，一名接受双硫仑治疗的患者出现严重的心血管虚脱，对多巴胺无反应，但用去甲肾上腺素成功逆转。对多巴胺的抵抗可能与双硫仑引起的去甲肾上腺素耗竭有关。因此，去甲肾上腺素可能是这些危及生命状况的首选治疗方法。