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Apparent progression of lentigo maligna to invasive melanoma during treatment with topical azelaic acid.

作者信息

McLean D I, Peter K K

出版信息

Br J Dermatol. 1986 Jun;114(6):685-9. doi: 10.1111/j.1365-2133.1986.tb04876.x.

DOI:10.1111/j.1365-2133.1986.tb04876.x
PMID:3718862
Abstract

Nine patients with lentigo maligna were treated with topical azelaic acid. Clinical improvement was observed in four, with complete clearing in one. Two patients developed invasive lentigo maligna melanoma while on treatment. Caution should be exercised in the use of topical azelaic acid in the treatment of lentigo maligna.

摘要

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引用本文的文献

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A possible mechanism of action for azelaic acid in the human epidermis.
壬二酸在人体表皮中的一种可能作用机制。
Arch Dermatol Res. 1990;282(3):168-71. doi: 10.1007/BF00372617.
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Azelaic acid. A review of its pharmacological properties and therapeutic efficacy in acne and hyperpigmentary skin disorders.壬二酸。对其药理学特性以及在痤疮和色素沉着性皮肤病中的治疗效果的综述。
Drugs. 1991 May;41(5):780-98. doi: 10.2165/00003495-199141050-00007.
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