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Sulforaphane Potentiates Gemcitabine-Mediated Anti-Cancer Effects against Intrahepatic Cholangiocarcinoma by Inhibiting HDAC Activity.蒜素通过抑制 HDAC 活性增强吉西他滨对肝内胆管癌的抗癌作用。
Cells. 2023 Feb 22;12(5):687. doi: 10.3390/cells12050687.
2
Shared and Related Molecular Targets and Actions of Salicylic Acid in Plants and Humans.水杨酸在植物和人类中的共享和相关分子靶标及作用。
Cells. 2023 Jan 4;12(2):219. doi: 10.3390/cells12020219.
3
Aglianico Grape Seed Semi-Polar Extract Exerts Anticancer Effects by Modulating MDM2 Expression and Metabolic Pathways.阿利根尼科葡萄籽油半极性提取物通过调节 MDM2 表达和代谢途径发挥抗癌作用。
Cells. 2023 Jan 4;12(2):210. doi: 10.3390/cells12020210.
4
Genome-Wide Analysis on Transcriptome and Methylome in Prevention of Mammary Tumor Induced by Early Life Combined Botanicals.基于转录组和甲基组的全基因组分析在预防早期生活联合植物诱发的乳腺肿瘤中的作用
Cells. 2022 Dec 21;12(1):14. doi: 10.3390/cells12010014.
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Tannic Acid, A Hydrolysable Tannin, Prevents Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition to Counteract Colorectal Tumor Growth.鞣酸,一种可水解的单宁,可防止转化生长因子-β诱导的上皮-间充质转化,从而抑制结直肠肿瘤生长。
Cells. 2022 Nov 17;11(22):3645. doi: 10.3390/cells11223645.
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Multi-Target Potential of Berberine as an Antineoplastic and Antimetastatic Agent: A Special Focus on Lung Cancer Treatment.小檗碱作为一种抗肿瘤和抗转移药物的多靶点潜力:特别关注肺癌治疗。
Cells. 2022 Oct 31;11(21):3433. doi: 10.3390/cells11213433.
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An Evaluation of the Novel Biological Properties of Diterpenes Isolated from Codd. In Vitro and In Silico.从 Codd 中分离出的二萜的新型生物学特性的评价:体外和计算机模拟。
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The Role of Natural Products and Their Multitargeted Approach to Treat Solid Cancer.天然产物及其治疗实体瘤的多靶点方法的作用。
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植物源生物活性物质在癌症治疗中的进展。

Advances in Plants-Derived Bioactives for Cancer Treatment.

机构信息

Faculty of Medicine, University of Porto, 4099-002 Porto, Portugal.

Institute for Research and Innovation in Health (i3S), University of Porto, 4099-002 Porto, Portugal.

出版信息

Cells. 2023 Apr 8;12(8):1112. doi: 10.3390/cells12081112.

DOI:10.3390/cells12081112
PMID:37190022
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10136607/
Abstract

Cancer, while a multifactorial chronic disease with an increasing prevalence, has been the subject of intense investigation, not only because of the growing need to find the main triggers that motivate its onset but essentially because of the need to discover increasingly safer and effective therapeutic options that have fewer adverse effects and associated toxicity [...].

摘要

癌症是一种多因素的慢性疾病,其发病率不断上升,一直是人们深入研究的课题,这不仅是因为人们越来越需要找到促使其发生的主要诱因,而且主要是因为需要发现越来越安全有效的治疗方法,这些方法的副作用和相关毒性更小。