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心力衰竭医学管理的经济毒性:JACC 本周综述主题。

Financial Toxicity of Medical Management of Heart Failure: JACC Review Topic of the Week.

机构信息

Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA. Electronic address: https://twitter.com/SmrithiSukumar.

Department of Medicine, Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, USA.

出版信息

J Am Coll Cardiol. 2023 May 23;81(20):2043-2055. doi: 10.1016/j.jacc.2023.03.402.

Abstract

Optimal medical management of heart failure (HF) improves quality of life, decreases mortality, and decreases hospitalizations. Cost may contribute to suboptimal adherence to HF medications, especially angiotensin receptor-neprilysin inhibitors and sodium-glucose cotransporter-2 inhibitors. Patients' experiences with HF medication cost include financial burden, financial strain, and financial toxicity. Although there has been research studying financial toxicity in patients with some chronic diseases, there are no validated tools for measuring financial toxicity of HF, and very few data on the subjective experiences of patients with HF and financial toxicity. Strategies to decrease HF-associated financial toxicity include making systemic changes to minimize cost sharing, optimizing shared decision-making, implementing policies to lower drug costs, broadening insurance coverage, and using financial navigation services and discount programs. Clinicians may also improve patient financial wellness through various strategies in routine clinical care. Future research is needed to study financial toxicity and associated patient experiences for HF.

摘要

心力衰竭(HF)的最佳药物治疗可改善生活质量,降低死亡率并减少住院率。成本可能导致 HF 药物治疗的依从性不理想,尤其是血管紧张素受体-脑啡肽酶抑制剂和钠-葡萄糖共转运蛋白-2 抑制剂。患者在 HF 药物费用方面的体验包括经济负担、经济压力和经济毒性。尽管已经有研究探讨了某些慢性病患者的经济毒性,但目前尚无用于测量 HF 经济毒性的经过验证的工具,并且关于 HF 患者的主观体验和经济毒性的数据也很少。降低 HF 相关经济毒性的策略包括进行系统改革以最大程度地减少费用分担,优化共同决策,实施降低药物成本的政策,扩大保险范围以及使用财务导航服务和折扣计划。临床医生也可以通过常规临床护理中的各种策略来改善患者的财务健康状况。需要进一步研究 HF 的经济毒性及其相关的患者体验。

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