Tajbakhsh Ardeshir, Salimi Sohrab, Daftarian Narsis, Abtahi Dariush
Department of Anesthesiology, School of Medicine, Anesthesiology Research Center, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Adv Biomed Res. 2023 Mar 21;12:59. doi: 10.4103/abr.abr_444_22. eCollection 2023.
Controversy remains about the positive role of music during general anesthesia and postoperative recovery. We, therefore, tested the hypothesis that intraoperative exposure to classical music reduces the propofol necessary to maintain the bispectral index (BIS) close to 50 during vitrectomy surgery.
This double-blind clinical study is evaluating 50 patients undergoing vitrectomy surgery under general anesthesia. Patients were randomly assigned to music and white noise groups, and relevant sounds were played to patients after induction of anesthesia. The two groups were compared for the use of propofol as an anesthetic to maintain a BIS near 50 and for postoperative pain, anxiety, nausea, and vomiting.
Propofol consumption to maintain the set BIS score was much lower in the music group than in the white noise group (78.72 ± 25.76 microgram/kg/min and 117.91 ± 36.78 microgram/kg/min, respectively, -value = 0.000). Postoperative pain scores were also much lower in the music group than in the white noise group (-value = 0.000) and anxiety levels between these two groups did not differ (-value = 0.870). No patient in the music group had complaints of postoperative nausea and vomiting (PONV) compared to six patients in the white noise group (-value = 0.011).
Listening to music during general anesthesia for vitrectomy surgery can reduce the use of anesthetics, postoperative pain, and PONV. Further, controlled studies are necessary to confirm our results.
关于音乐在全身麻醉及术后恢复过程中的积极作用仍存在争议。因此，我们检验了以下假设：在玻璃体切除手术中，术中暴露于古典音乐环境下可减少维持脑电双频指数（BIS）接近50所需的丙泊酚用量。
这项双盲临床研究评估了50例在全身麻醉下接受玻璃体切除手术的患者。患者被随机分为音乐组和白噪声组，麻醉诱导后向患者播放相应声音。比较两组维持BIS接近50时丙泊酚作为麻醉剂的使用情况以及术后疼痛、焦虑、恶心和呕吐情况。
维持设定BIS评分时，音乐组的丙泊酚消耗量显著低于白噪声组（分别为78.72±25.76微克/千克/分钟和117.91±36.78微克/千克/分钟，P值=0.000）。音乐组的术后疼痛评分也显著低于白噪声组（P值=0.000），且两组间焦虑水平无差异（P值=0.870）。音乐组无患者出现术后恶心呕吐（PONV），而白噪声组有6例患者出现（P值=0.011）。
玻璃体切除手术全身麻醉期间听音乐可减少麻醉剂使用、术后疼痛及PONV。此外，需要进行对照研究以证实我们的结果。
