Tian Siyu, Zhang Hang, Chen Siqi, Wu Pengning, Chen Min
School of Clinical Medicine, Chengdu University of TCM, Chengdu, China.
Department of Colorectal Diseases, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Front Pharmacol. 2023 May 2;14:1175057. doi: 10.3389/fphar.2023.1175057. eCollection 2023.
Irritable bowel syndrome (IBS) is a group of functional intestinal disorders characterized by abdominal pain, bloating, and changes in bowel habits, and/or stool characteristics. Recent studies have shown that there has been a significant advancement in the study of visceral hypersensitivity in IBS. Through the use of bibliometrics, this study aims to provide a comprehensive overview of the knowledge structure and research hotpots of visceral hypersensitivity in IBS. Publications related to visceral hypersensitivity in IBS from 2012 to 2022 were searched on the web of science core collection (WoSCC) database. CiteSpace.6.1. R2 and Vosviewer 1.6.17 were used to perform bibliometric analysis. A total of 974 articles led by China and the United States from 52 countries were included. Over the past decade, the number of articles on visceral hypersensitivity and IBS has steadily increased year by year. China, the United States, and Belgium are the main countries in this field. Univ Oklahoma, Univ Gothenburg, and Zhejiang University are the main research institutions. Simren, Magnus, Greenwood-van meerveld, Beverley, and Tack, Jan are the most published authors in this research field. The research on the causes, genes, and pathways involved in visceral hypersensitivity in IBS and the mechanism of IBS are the main topics and hotspots in this field. This study also found that gut microbiota may be related to the occurrence of visceral hypersensitivity, and probiotics may be a new method for the treatment of visceral hypersensitivity and pain, which may become a new direction for research in this field. This is the first bibliometric study to comprehensively summarize the research trends and developments of visceral hypersensitivity in IBS. This information provides the research frontier and hot topics in this field in recent years, which will provide a reference for scholars studying this field.
肠易激综合征（IBS）是一组功能性肠道疾病，其特征为腹痛、腹胀、排便习惯改变和/或大便性状改变。最近的研究表明，IBS内脏高敏感性的研究有了显著进展。通过文献计量学方法，本研究旨在全面概述IBS内脏高敏感性的知识结构和研究热点。在科学网核心合集（WoSCC）数据库中检索了2012年至2022年与IBS内脏高敏感性相关的出版物。使用CiteSpace.6.1.R2和Vosviewer 1.6.17进行文献计量分析。共纳入了来自52个国家的974篇由中国和美国牵头的文章。在过去十年中，关于内脏高敏感性和IBS的文章数量逐年稳步增加。中国、美国和比利时是该领域的主要国家。俄克拉荷马大学、哥德堡大学和浙江大学是主要研究机构。Simren、Magnus；Greenwood-van meerveld、Beverley；以及Tack、Jan是该研究领域发表文章最多的作者。IBS内脏高敏感性的病因、基因和相关通路以及 IBS的发病机制是该领域的主要主题和热点。本研究还发现，肠道微生物群可能与内脏高敏感性的发生有关，益生菌可能是治疗内脏高敏感性和疼痛的新方法，这可能成为该领域的新研究方向。这是第一项全面总结IBS内脏高敏感性研究趋势和进展的文献计量学研究。这些信息提供了该领域近年来的研究前沿和热点话题，将为研究该领域的学者提供参考。
