Park Byung Kyu, Koh Hee Dong, Won Sun Young, Cho Yong Suk, Seo Jeong Hun, An Chansik, Park Sumi
Division of Gastroenterology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
Department of Radiology, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
J Gastrointest Oncol. 2023 Apr 29;14(2):1008-1018. doi: 10.21037/jgo-22-863. Epub 2023 Mar 23.
Few studies have focused on computed tomography findings before a pancreatic cancer diagnosis. We aimed to investigate the prediagnostic computed tomography findings of patients who had undergone computed tomography within the prediagnostic period of their pancreatic cancer diagnosis.
Between January 2008 and December 2019, 27 patients who underwent contrast-enhanced abdominal or chest computed tomography including the pancreas within 1 year of a pancreatic cancer diagnosis were enrolled in this retrospective study. The prediagnostic computed tomography imaging findings were divided into pancreatic parenchyma and pancreatic duct findings.
All patients underwent computed tomography for reasons unrelated to pancreatic cancer. The pancreatic parenchyma and ducts showed normal findings in seven patients and abnormal findings in 20 patients. Hypoattenuating mass-like lesions were detected in nine patients with a median size of 1.2 cm. Six patients had focal pancreatic duct dilatations, and two patients had distal parenchymal atrophy. In three patients, two of these findings were found simultaneously. Taken together, 14 (51.9%) of 27 patients had findings suggestive of pancreatic cancer in prediagnostic computed tomography.
In contrast-enhanced computed tomography performed for other purposes, attention should be paid to the presence of a hypoattenuating mass, focal pancreatic duct dilatation, or distal parenchymal atrophy of the pancreas. These features may be clues for an early diagnosis of pancreatic cancer.
很少有研究关注胰腺癌诊断前的计算机断层扫描（CT）结果。我们旨在调查在胰腺癌诊断的预诊断期内接受过CT检查的患者的预诊断CT结果。
在2008年1月至2019年12月期间，本回顾性研究纳入了27例在胰腺癌诊断后1年内接受了包括胰腺在内的腹部或胸部增强CT检查的患者。将预诊断CT影像结果分为胰腺实质和胰管结果。
所有患者接受CT检查的原因均与胰腺癌无关。7例患者的胰腺实质和胰管表现正常，20例患者表现异常。9例患者检测到低密度肿块样病变，中位大小为1.2 cm。6例患者有局灶性胰管扩张，2例患者有远端实质萎缩。在3例患者中，同时发现了其中两种表现。总体而言，27例患者中有14例（51.9%）在预诊断CT中出现提示胰腺癌的表现。
在为其他目的进行的增强CT检查中，应注意胰腺是否存在低密度肿块、局灶性胰管扩张或远端实质萎缩。这些特征可能是早期诊断胰腺癌的线索。
