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[一级护理单元宫颈发育异常的流行病学全景]

[Epidemiological Panorama of Cervical Dysplasia in a First-Level Care Unit].

作者信息

Seefoó-Jarquín Patricia, Sosa-Jurado Francisca, Maycotte-González Paola

机构信息

Instituto Mexicano del Seguro Social, Hospital General de Zona, Unidad de Medicina Familiar No. 8. Tlaxcala, Tlaxcala, México.

Instituto Mexicano del Seguro Social, Órgano de Operación Administrativa Desconcentrada Puebla, Centro de Investigación Biomédica de Oriente. Metepec, Puebla, México.

出版信息

Rev Med Inst Mex Seguro Soc. 2023 Mar 1;61(2):155-162.

Abstract

BACKGROUND

Cervical cancer (CaCU) is the second cancer-related cause of death for women in Mexico. Early diagnosis and monitoring of patients by cervical cytology and colposcopy are currently the preferred screening methods for identification and prevention of this disease.

OBJECTIVE

To describe the epidemiological panorama of cervical dysplasia diagnosed in a first-level care hospital.

METHODS

The study was observational, retrospective, unicentric, homodemic, transversal. Records from 6,207 women who attended the General Subzone Hospital with Familiar Medicine #8 (HGSZ/UMF 8), in Tlaxcala, Mexico were analyzed. First-time cervical cytologies were analyzed from 2019 to 2021.

RESULTS

Cervical dysplasia was found in 2.6% of the patients being the most frequent type of dysplasia NIC 1. Most of the clinical characteristics of patients with dysplasia were in agreement with those of the Mexican population. Important differences were found (comorbilities, mass index, number of sexual partners, births, positivity to changes related to HPV and vaccination) between two population sets defined by age (younger and older than 40 years).

CONCLUSIONS

The only factor where a tendency to be associated to type 2 and 3 dysplasia in the population younger than 40 years was the sexually active onset of life younger than 18 years, so this possible association should be evaluated in a bigger population. Our data suggests that risks factors should be evaluated separately for these age groups due to important differences regarding their clinic and epidemiological characteristics as well as changes in risk factor exposure.

摘要

背景

宫颈癌是墨西哥女性癌症相关死亡的第二大原因。目前,通过宫颈细胞学检查和阴道镜检查对患者进行早期诊断和监测是识别和预防该疾病的首选筛查方法。

目的

描述在一级护理医院诊断出的宫颈发育异常的流行病学概况。

方法

该研究为观察性、回顾性、单中心、同地区、横断面研究。分析了墨西哥特拉斯卡拉市第8号家庭医学综合分区医院(HGSZ/UMF 8)6207名女性的记录。对2019年至2021年的首次宫颈细胞学检查进行了分析。

结果

2.6%的患者发现有宫颈发育异常,最常见的发育异常类型为NIC 1。发育异常患者的大多数临床特征与墨西哥人群一致。在按年龄定义的两个人群组(40岁以下和40岁以上)之间发现了重要差异(合并症、体重指数、性伴侣数量、生育情况、HPV相关变化和疫苗接种的阳性率)。

结论

在40岁以下人群中,唯一与2级和3级发育异常有相关趋势的因素是18岁之前开始性活动,因此这种可能的关联应在更大的人群中进行评估。我们的数据表明,由于这些年龄组在临床和流行病学特征以及危险因素暴露方面存在重要差异,应分别评估这些年龄组的危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0137/10395894/1402e715914f/04435117-61-2-155-c001.jpg

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