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[宫颈上皮内瘤变发生的妇产科及社会因素]

[Obstetric-gynecological and social factors for the development of cervical intraepithelial neoplasia].

作者信息

Villanueva-Duque José Alfredo, Castro-Valdés Isis Carolina, García-Cervantes Nancy

机构信息

Instituto Mexicano del Seguro Social, Unidad de Medicina Familiar No. 15, Coordinación Clínica de Educación e Investigación en Salud. Ciudad de México, México.

Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Centro de Investigación Educativa y Formación Docente. Ciudad de México, México.

出版信息

Rev Med Inst Mex Seguro Soc. 2024 Sep 2;62(5):1-7. doi: 10.5281/zenodo.12667984.

Abstract

BACKGROUND

Cervical intraepithelial neoplasia (CIN) precedes cervical cancer and it is associated with risk factors that can be identified in the population, which contribute to timely diagnosis and treatment.

OBJECTIVE

To identify associated risk factors for the development of CIN in women attended at the first level of care.

MATERIAL AND METHODS

A cross-sectional and retrospective study was conducted in women in the 2020-2022 period. Frequencies and means were obtained. For the differences, chi-squared and Student's t were used. Odds ratios (OR) were obtained to assess the risk.

RESULTS

ORs were determined in the group of women with CIN II/CIN III, obtaining risks of almost twice the risk factors analyzed compared to the CIN I group, which had the same factors. When analyzed by age groups < or > 40 years, significant associations were determined in the factors of parity, first cytology in life and positive for smoking. In the group < 40 years and with CIN II/III significant risks were determined in age at first pregnancy < 18 (OR 8.33), first cytology in life (OR 3.77), positive for smoking (OR 3.0), sexual intercourse initiation (SII) before 18 years of age (OR 3.1) and parity (OR 1.3).

CONCLUSIONS

According to the results obtained, sexual and reproductive behavioral factors are of high risk for the development of CIN.

摘要

背景

宫颈上皮内瘤变(CIN)先于宫颈癌,且与人群中可识别的危险因素相关,这些因素有助于及时诊断和治疗。

目的

确定在一级医疗机构就诊的女性发生CIN的相关危险因素。

材料与方法

对2020 - 2022年期间的女性进行了一项横断面回顾性研究。获取了频率和均值。对于差异,使用了卡方检验和学生t检验。获得优势比(OR)以评估风险。

结果

在CIN II/CIN III组女性中确定了优势比,与具有相同因素的CIN I组相比,所分析的危险因素风险几乎高出两倍。按年龄组<或>40岁进行分析时,在产次、首次细胞学检查和吸烟阳性因素中确定了显著关联。在<40岁且患有CIN II/III的组中,首次怀孕年龄<18岁(OR 8.33)、首次细胞学检查(OR 3.77)、吸烟阳性(OR 3.0)、18岁之前开始性行为(SII)(OR 3.1)和产次(OR 1.3)存在显著风险。

结论

根据所得结果,性和生殖行为因素是发生CIN的高风险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9dd/12410974/4dcac34e31b6/04435117-62-5-e5848-c001.jpg

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