Baldwin David R, O'Dowd Emma L, Tietzova Ilona, Kerpel-Fronius Anna, Heuvelmans Marjolein A, Snoeckx Annemiek, Ashraf Haseem, Kauczor Hans-Ulrich, Nagavci Blin, Oudkerk Matthijs, Putora Paul Martin, Ryzman Witold, Veronesi Giulia, Borondy-Kitts Andrea, Rosell Gratacos Antoni, van Meerbeeck Jan, Blum Torsten G
Department of Respiratory Medicine, Nottingham University Hospitals NHS Trust, Nottingham, UK
Epidemiology and Public Health, University of Nottingham, Nottingham, UK.
Eur Respir J. 2023 Jun 15;61(6). doi: 10.1183/13993003.00128-2023. Print 2023 Jun.
Screening for lung cancer with low radiation dose computed tomography (LDCT) has a strong evidence base. The European Council adopted a recommendation in November 2022 that lung cancer screening (LCS) be implemented using a stepwise approach. The imperative now is to ensure that implementation follows an evidence-based process that delivers clinical and cost-effectiveness. This European Respiratory Society (ERS) Task Force was formed to provide a technical standard for a high-quality LCS programme.
A collaborative group was convened to include members of multiple European societies. Topics were identified during a scoping review and a systematic review of the literature was conducted. Full text was provided to members of the group for each topic. The final document was approved by all members and the ERS Scientific Advisory Committee.
Topics were identified representing key components of a screening programme. The actions on findings from the LDCT were not included as they are addressed by separate international guidelines (nodule management and clinical management of lung cancer) and by a linked ERS Task Force (incidental findings). Other than smoking cessation, other interventions that are not part of the core screening process were not included ( pulmonary function measurement). 56 statements were produced and areas for further research identified.
This European collaborative group has produced a technical standard that is a timely contribution to implementation of LCS. It will serve as a standard that can be used, as recommended by the European Council, to ensure a high-quality and effective programme.
低剂量计算机断层扫描（LDCT）筛查肺癌有强有力的证据基础。欧洲理事会于2022年11月通过了一项建议，即采用逐步推进的方法实施肺癌筛查（LCS）。当务之急是确保实施过程遵循基于证据的流程，以实现临床和成本效益。成立了欧洲呼吸学会（ERS）特别工作组，以提供高质量LCS计划的技术标准。
召集了一个合作小组，成员包括多个欧洲学会的成员。在范围界定审查期间确定了主题，并对文献进行了系统综述。为小组的每个成员提供了每个主题的全文。最终文件得到了所有成员和ERS科学咨询委员会的批准。
确定了代表筛查计划关键组成部分的主题。由于单独的国际指南（结节管理和肺癌临床管理）以及相关的ERS特别工作组（偶然发现）已对LDCT检查结果的处理进行了阐述，因此未将其纳入。除戒烟外，未包括其他不属于核心筛查过程的干预措施（肺功能测量）。制定了56条声明，并确定了进一步研究的领域。
这个欧洲合作小组制定了一项技术标准，为LCS的实施做出了及时贡献。它将作为一项标准，按照欧洲理事会的建议使用，以确保高质量和有效的计划。
