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Case for diagnosis. Disseminated erythematous and scaly plaques: chronic mucocutaneous candidiasis.

作者信息

Abreu Nathalia Chebli de, França Samuel Duarte Timponi, Marcelo Júnior Hyllo Baeta, Ladeira Amanda Neto

机构信息

Department of Dermatology, Hospital Infantil João Paulo II, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, MG, Brazil; Department of Dermatology, Hospital Eduardo de Menezes, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, MG, Brazil.

Department of Dermatology, Hospital Infantil João Paulo II, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, MG, Brazil; Department of Dermatology, Hospital Eduardo de Menezes, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, MG, Brazil.

出版信息

An Bras Dermatol. 2023 Sep-Oct;98(5):691-694. doi: 10.1016/j.abd.2022.08.013. Epub 2023 May 16.

DOI:10.1016/j.abd.2022.08.013
PMID:37202247
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10404544/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61b6/10404544/cddc931772d9/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61b6/10404544/ea86f7be5412/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61b6/10404544/747d412f07f1/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61b6/10404544/4999a612b00d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61b6/10404544/cddc931772d9/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61b6/10404544/ea86f7be5412/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61b6/10404544/747d412f07f1/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61b6/10404544/4999a612b00d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61b6/10404544/cddc931772d9/gr4.jpg

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本文引用的文献

1
Primary immunodeficiency and chronic mucocutaneous candidiasis: pathophysiological, diagnostic, and therapeutic approaches.原发性免疫缺陷病和慢性黏膜皮肤念珠菌病：病理生理学、诊断和治疗方法。
Allergol Immunopathol (Madr). 2021 Jan 2;49(1):118-127. doi: 10.15586/aei.v49i1.20. eCollection 2021.
2
Baricitinib treatment in a patient with a gain-of-function mutation in signal transducer and activator of transcription 1 (STAT1).巴瑞替尼治疗一名信号转导和转录激活因子1（STAT1）功能获得性突变患者。
J Allergy Clin Immunol. 2018 Jul;142(1):328-330.e2. doi: 10.1016/j.jaci.2018.02.045. Epub 2018 May 2.
3
Treatment options for chronic mucocutaneous candidiasis.
慢性黏膜皮肤念珠菌病的治疗选择。
J Infect. 2016 Jul 5;72 Suppl:S56-60. doi: 10.1016/j.jinf.2016.04.023. Epub 2016 May 6.
4
Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype.杂合性信号转导和转录激活因子1（STAT1）功能获得性突变是一种临床表型出人意料广泛的疾病的基础。
Blood. 2016 Jun 23;127(25):3154-64. doi: 10.1182/blood-2015-11-679902. Epub 2016 Apr 25.
5
Use of ruxolitinib to successfully treat chronic mucocutaneous candidiasis caused by gain-of-function signal transducer and activator of transcription 1 (STAT1) mutation.使用鲁索替尼成功治疗由功能获得性信号转导和转录激活因子1（STAT1）突变引起的慢性黏膜皮肤念珠菌病。
J Allergy Clin Immunol. 2015 Feb;135(2):551-3. doi: 10.1016/j.jaci.2014.12.1867.
6
STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis.常染色体显性遗传慢性黏膜皮肤念珠菌病中的 STAT1 突变。
N Engl J Med. 2011 Jul 7;365(1):54-61. doi: 10.1056/NEJMoa1100102. Epub 2011 Jun 29.
7
Patients with chronic mucocutaneous candidiasis exhibit reduced production of Th17-associated cytokines IL-17 and IL-22.慢性黏膜皮肤念珠菌病患者的Th17相关细胞因子IL-17和IL-22产生减少。
J Invest Dermatol. 2008 Nov;128(11):2640-2645. doi: 10.1038/jid.2008.139. Epub 2008 Jul 10.
8
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Neth J Med. 2003 Nov;61(11):365-9.
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