Kirkpatrick C H
Department of Medicine, University of Colorado Health Sciences Center, Denver.
J Am Acad Dermatol. 1994 Sep;31(3 Pt 2):S14-7. doi: 10.1016/s0190-9622(08)81260-1.
Chronic mucocutaneous candidiasis is a complex disorder in which patients have chronic and recurrent Candida albicans infections of the skin, nails, and mucous membranes. There are several subgroups of patients with chronic mucocutaneous candidiasis, and these can be identified by associated disorders such as autoimmune diseases, endocrinopathies, thymoma, and interstitial keratitis, as well as the distribution and severity of the Candida infections. Several other disorders may coexist in patients with chronic mucocutaneous candidiasis. These include other infectious diseases, endocrinopathies, dental enamel dysplasia, vitiligo, and alopecia totalis. Successful treatment programs should include antifungal drugs and manipulations that correct the immunologic abnormalities that predispose the patient to Candida infections.
慢性黏膜皮肤念珠菌病是一种复杂的病症，患者的皮肤、指甲和黏膜会出现慢性复发性白色念珠菌感染。慢性黏膜皮肤念珠菌病患者有几个亚组，可通过自身免疫性疾病、内分泌病、胸腺瘤和间质性角膜炎等相关病症以及念珠菌感染的分布和严重程度来识别。慢性黏膜皮肤念珠菌病患者可能还并存其他几种病症。这些病症包括其他传染病、内分泌病、牙釉质发育不全、白癜风和全秃。成功的治疗方案应包括抗真菌药物以及纠正使患者易患念珠菌感染的免疫异常的措施。
